Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | CES1 | P23141 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL124577 | 0.98 | KMT2A (0.59) | KMT2AMEN1NPC1SMN1; SMN2KDM4E | |
| SCHEMBL17433632 | 0.96 | KMT2A (0.57) | KMT2AMEN1NPC1SMN1; SMN2KDM4E | |
| SCHEMBL17433663 | 0.96 | KMT2A (0.57) | KMT2AMEN1NPC1SMN1; SMN2KDM4E | |
| SCHEMBL28048836 | 0.96 | KMT2A (0.57) | KMT2AMEN1NPC1SMN1; SMN2KDM4E | |
| SCHEMBL28792148 | 0.96 | KMT2A (0.57) | KMT2AMEN1NPC1SMN1; SMN2KDM4E | |
| SCHEMBL17433560 | 0.96 | KMT2A (0.57) | KMT2AMEN1NPC1SMN1; SMN2KDM4E | |
| SCHEMBL31439645 | 0.96 | KMT2A (0.57) | KMT2AMEN1NPC1SMN1; SMN2KDM4E | |
| SCHEMBL28048838 | 0.96 | KMT2A (0.57) | KMT2AMEN1NPC1SMN1; SMN2KDM4E | |
| SCHEMBL17433641 | 0.96 | KMT2A (0.57) | KMT2AMEN1NPC1SMN1; SMN2KDM4E | |
| SCHEMBL28048832 | 0.96 | KMT2A (0.57) | KMT2AMEN1NPC1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116554029-B | Synthesis method of aromatic formyl ethyl acetate | 河北民族师范学院 | 2024-03-29 | — | — | CN | disclosed |
| CN-116554029-A | Synthesis method of aromatic formyl ethyl acetate | 河北民族师范学院 | 2023-08-08 | — | — | CN | disclosed |
| CN-101624519-B | Preparation and application of pyrazolone-shrinking phenyl semicarbazide photochromic compounds | UNIV XINJIANG | 2012-08-08 | — | — | CN | disclosed |
| CN-101624519-A | Preparation and application of pyrazolone-shrinking phenyl semicarbazide photochromic compounds | UNIV XINJIANG | 2010-01-13 | — | — | CN | disclosed |
| US-6706748-B2 | USE AS MICROBICIDES | NIHON BAYER AGROCHEM, K.K. (JP) | 2004-03-16 | — | — | US | disclosed |
| US-20030220197-A1 | Isothiazole derivatives | NIHON BAYER AGROCHEM K.K. (JP) | 2003-11-27 | — | — | US | disclosed |
| EP-1284970-A2 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2003-02-26 | — | — | EP | disclosed |
| WO-2001077090-A2 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-10-18 | — | — | WO | disclosed |
| US-4996120-A | Free radical polymerization upon exposure to actinic radiation | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |
| US-4959284-A | Holographic photopolymer compositions and elements containing a ring-opening monomer | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-09-25 | — | — | US | disclosed |
| EP-0377182-A2 | Improved holographic photopolymer compositions and elements containing a ring-opening monomer | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220197-A1 | Isothiazole derivatives | IRF3, MSR1, ARG1 | KMT2A 3359/4885MEN1 4222/4885NPC1 566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.