Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29877981 | 0.78 | KDM4E (0.32) | KDM4EALDH1A1POLB | |
| SCHEMBL30202196 | 0.76 | KDM4E (0.32) | KDM4EALDH1A1POLB | |
| SCHEMBL34468447 | 0.69 | USP8 (0.33) | KDM4EALDH1A1POLB | |
| SCHEMBL13480742 | 0.69 | CCR1 (0.38) | KDM4EALDH1A1POLB | |
| SCHEMBL480214 | 0.68 | PIK3CD (0.33) | KDM4EALDH1A1POLB | |
| SCHEMBL2076123 | 0.68 | CHEK1 (0.37) | KDM4EALDH1A1POLB | |
| SCHEMBL1841305 | 0.68 | CCR1 (0.35) | ALDH1A1POLB | |
| SCHEMBL15666218 | 0.65 | ERBB2 (0.32) | — | |
| SCHEMBL17416926 | 0.65 | KDM4E (0.33) | KDM4EALDH1A1POLB | |
| SCHEMBL18956948 | 0.65 | KDM4E (0.36) | KDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440245-A1 | BENZONAPHTHYRIDINE-CONTAINING VACCINES | Novartis AG (CH) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010144734-A1 | BENZONAPHTHYRIDINE-CONTAINING VACCINES | NOVARTIS AG (CH) | 2010-12-16 | — | — | WO | disclosed |