Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | CCR8 | P51685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13480742 | 0.80 | CCR1 (0.38) | KDM4EALDH1A1POLBCCR1CCR5 | |
| SCHEMBL1703322 | 0.76 | KDM4E (0.31) | KDM4EALDH1A1POLB | |
| SCHEMBL16836800 | 0.75 | KDM4E (0.40) | KDM4EALDH1A1POLBCCR1CCR5 | |
| SCHEMBL14438199 | 0.72 | CCR1 (0.37) | CCR1CCR5CCR8 | |
| SCHEMBL24039918 | 0.72 | KDM4E (0.34) | KDM4EALDH1A1POLB | |
| SCHEMBL34468447 | 0.72 | USP8 (0.33) | KDM4EALDH1A1POLB | |
| SCHEMBL21938067 | 0.72 | KDM4E (0.34) | KDM4EALDH1A1POLB | |
| SCHEMBL7672194 | 0.72 | AGXT (0.46) | KDM4EALDH1A1POLB | |
| SCHEMBL2076123 | 0.71 | CHEK1 (0.37) | KDM4EALDH1A1POLB | |
| SCHEMBL8870206 | 0.69 | HSP90AA1 (0.34) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4387609-A2 | ARYL SULFONYL (HYDROXY) PIPERIDINES AS CCR6 INHIBITORS | ChemoCentryx, Inc. (US) | 2024-06-26 | — | — | EP | disclosed |
| WO-2023023532-A2 | ARYL SULFONYL (HYDROXY) PIPERIDINES AS CCR6 INHIBITORS | CHEMOCENTRYX, INC. (US) | 2023-02-23 | — | — | WO | disclosed |