SCHEMBL17033508

SCHEMBL17033508

c1ccc(-c2ccc(-c3cc(-c4ccc(-c5ccccn5)cc4)nc(-n4c5ccccc5c5cc6c(cc54)cc4c5ccccc5c5ccccc5n64)n3)cc2)nc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPY5R Q15761 2/20 0.40
DHODH Q02127 1/20 0.39
METAP2 P50579 3/20 0.34
MCL1 Q07820 3/20 0.33
AURKA O14965 1/20 0.33
CHEK2 O96017 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MAPT P10636 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
PPP1CA P62136 1/20 0.32
KMT2A Q03164 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
KDM4E B2RXH2 1/20 0.31
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17033420 0.97 NPY5R (0.39) NPY5RDHODHMETAP2MCL1AURKA
SCHEMBL17033514 0.92 NPY5R (0.39) NPY5RDHODHMETAP2MCL1AURKA
SCHEMBL17033414 0.89 NPY5R (0.39) NPY5RDHODHMETAP2MCL1AURKA
SCHEMBL17033502 0.88 L3MBTL1 (0.35) NPY5RDHODHAURKATSHRMAPK1
SCHEMBL17033483 0.88 L3MBTL1 (0.35) NPY5RTSHRMAPK1HSD17B10MAPT
SCHEMBL17033800 0.88 DHODH (0.38) NPY5RDHODHMETAP2MCL1AURKA
SCHEMBL17033542 0.86 MAPK1 (0.41) TSHRMAPK1HSD17B10MAPTCYP1A2
SCHEMBL17033532 0.86 NPY5R (0.36) NPY5RMETAP2MCL1TSHRMAPT
SCHEMBL17033750 0.85 DHODH (0.38) NPY5RDHODHMETAP2MCL1AURKA
SCHEMBL16066977 0.85 DHODH (0.41) NPY5RDHODHTSHRMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015125986-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-08-27 WO disclosed