SCHEMBL17033683

SCHEMBL17033683

Fc1ccc(-c2cc(-c3ccc(F)cc3)nc(-n3c4ccccc4c4cc5nc6c7ccccc7c7ccccc7n6c5cc43)n2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
HPGD P15428 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
KMT2A Q03164 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.39
MAPT P10636 2/20 0.39
HTT P42858 2/20 0.39
MAPK1 P28482 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
CYP19A1 P11511 1/20 0.38
KDM4E B2RXH2 6/20 0.34
ACP1 P24666 3/20 0.33
GRM2 Q14416 1/20 0.33
LMNA P02545 2/20 0.32
HSD17B10 Q99714 2/20 0.32
TP53 P04637 1/20 0.32
POLB P06746 1/20 0.32
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17033710 0.91 KDM4E (0.40) ALDH1A1HPGDSMN1; SMN2KMT2AL3MBTL1
SCHEMBL16067119 0.90 ALDH1A1 (0.50) ALDH1A1HPGDSMN1; SMN2KMT2AL3MBTL1
SCHEMBL16066947 0.89 ALDH1A1 (0.51) ALDH1A1HPGDSMN1; SMN2KMT2AL3MBTL1
SCHEMBL17033685 0.87 DHODH (0.38) ALDH1A1HPGDSMN1; SMN2KMT2AMAPT
SCHEMBL17033408 0.83 MAPK1 (0.41) ALDH1A1HPGDSMN1; SMN2KMT2AL3MBTL1
SCHEMBL17033542 0.82 MAPK1 (0.41) ALDH1A1HPGDSMN1; SMN2KMT2AL3MBTL1
SCHEMBL16067107 0.81 KDM4E (0.45) ALDH1A1HPGDSMN1; SMN2KMT2AL3MBTL1
SCHEMBL17033707 0.81 HPGD (0.41) ALDH1A1HPGDSMN1; SMN2KMT2AMAPT
SCHEMBL16066506 0.81 KDM4E (0.47) ALDH1A1HPGDSMN1; SMN2KMT2AL3MBTL1
SCHEMBL17033763 0.81 KDM4E (0.43) ALDH1A1HPGDSMN1; SMN2KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015125986-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-08-27 WO disclosed