SCHEMBL17033739

SCHEMBL17033739

c1ccc(-c2ccc(-c3nc(-c4ccc(-c5ccccn5)cc4)nc(-n4c5ccccc5c5ccc6c(cc7c8ccccc8c8ccccc8n76)c54)n3)cc2)nc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.35
NPY5R Q15761 1/20 0.35
MCL1 Q07820 5/20 0.34
KDM4E B2RXH2 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
MAPT P10636 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
PPP1CA P62136 1/20 0.33
KMT2A Q03164 1/20 0.33
TSHR P16473 2/20 0.32
HSD17B10 Q99714 2/20 0.32
SLC6A7 Q99884 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
PKM P14618 1/20 0.32
KLF5 Q13887 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17033768 0.94 NPY5R (0.37) DHODHNPY5RMCL1KDM4ETDP1
SCHEMBL17033750 0.92 DHODH (0.38) DHODHNPY5RMCL1MAPTNPSR1
SCHEMBL17033445 0.92 MCL1 (0.35) NPY5RMCL1KDM4ETDP1MAPT
SCHEMBL17033653 0.88 MCL1 (0.36) DHODHNPY5RMCL1KDM4ETDP1
SCHEMBL17033769 0.88 DHODH (0.37) DHODHNPY5RMCL1KDM4EMAPT
SCHEMBL17033798 0.87 DHODH (0.35) DHODHNPY5RMCL1KDM4ETDP1
SCHEMBL17033775 0.86 MEN1 (0.33) NPY5RKDM4EMAPTKMT2ATSHR
SCHEMBL17033444 0.86 KDM4E (0.33) KDM4ETDP1MAPTNPSR1KMT2A
SCHEMBL17033514 0.86 NPY5R (0.39) DHODHNPY5RMCL1KDM4ETDP1
SCHEMBL17033745 0.84 HTR1A (0.35) DHODHNPY5RMCL1TSHRMETAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015125986-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-08-27 WO disclosed