SCHEMBL17033874

SCHEMBL17033874

c1ccc(-c2ccc(-c3cccc(-c4cc(-n5c6ccccc6c6ccc7c(nc8c9ccccc9c9ccccc9n78)c65)ncn4)c3)cc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMO O15229 1/20 0.34
LIMK1 P53667 1/20 0.33
NPC1 O15118 1/20 0.32
TSHR P16473 1/20 0.32
RECQL P46063 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HRH4 Q9H3N8 1/20 0.31
DPP4 P27487 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17033881 0.99 KMO (0.35) KMOLIMK1NPC1TSHRRECQL
SCHEMBL17033880 0.87
SCHEMBL17033696 0.85 KDM4E (0.32) TSHR
SCHEMBL17033873 0.85 KMO (0.38) KMOLIMK1NPC1TSHRRECQL
SCHEMBL17033904 0.84 KMO (0.38) KMOLIMK1NPC1TSHRRECQL
SCHEMBL17033717 0.84 PDE4A (0.36) TSHRSMN1; SMN2
SCHEMBL17033894 0.83 LIMK1 (0.33) LIMK1
SCHEMBL17033721 0.83 POLB (0.32)
SCHEMBL17033872 0.83 PIK3CA (0.34)
SCHEMBL17033871 0.82 LIMK1 (0.32) LIMK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015125986-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-08-27 WO disclosed