SCHEMBL17034394

SCHEMBL17034394

Cn1c2ccc(-c3ccc4c(c3)c3ccccc3n4-c3ccccc3)cc2c2ccc(C#N)cc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 7/20 0.44
▸ KDM4E B2RXH2 4/20 0.44
▸ ATM Q13315 1/20 0.44
▸ RXRA P19793 1/20 0.43
▸ RXRB P28702 1/20 0.43
▸ PTGER4 P35408 1/20 0.41
▸ MEN1 O00255 3/20 0.40
▸ KMT2A Q03164 3/20 0.40
▸ TLR9 Q9NR96 1/20 0.40
▸ GPR3 P46089 1/20 0.39
▸ ALDH1A1 P00352 2/20 0.39
▸ HPGD P15428 2/20 0.39
▸ HSD17B10 Q99714 2/20 0.39
▸ MAPT P10636 2/20 0.39
▸ HTT P42858 1/20 0.39
▸ KIF11 P52732 1/20 0.38
▸ PGR P06401 1/20 0.38
▸ POLB P06746 1/20 0.37
▸ PTPN7 P35236 1/20 0.37
▸ DUSP3 P51452 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17034473 0.95 KDM4E (0.46) L3MBTL1KDM4EATMRXRARXRB
SCHEMBL17032707 0.93 PTGER4 (0.40) L3MBTL1KDM4EATMRXRARXRB
SCHEMBL20251580 0.91 KDM4E (0.50) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL17660975 0.90 KDM4E (0.49) L3MBTL1KDM4EATMPTGER4PGR
SCHEMBL18623543 0.89 KDM4E (0.47) L3MBTL1KDM4EATMPTGER4PGR
SCHEMBL18633415 0.89 KDM4E (0.47) L3MBTL1KDM4EATMPTGER4PGR
SCHEMBL29512060 0.88 KDM4E (0.53) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL15248340 0.88 KDM4E (0.53) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL17034483 0.88 PTGER4 (0.41) L3MBTL1KDM4EATMRXRARXRB
SCHEMBL17032736 0.88 KDM4E (0.46) L3MBTL1KDM4EATMPTGER4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230131934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 — — US disclosed
US-10403825-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-09-03 — — US disclosed
US-20150243903-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-08-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10403825-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, OSBP L3MBTL1 930/4885KDM4E 4278/4885ATM 4635/4885
US-20150243903-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP L3MBTL1 930/4885KDM4E 4278/4885ATM 4635/4885
US-20230131934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP L3MBTL1 930/4885KDM4E 4278/4885ATM 4635/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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