Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 9/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | MDH2 | P40926 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15840228 | 0.84 | KIF11 (0.49) | KIF11NPC1ALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL17050080 | 0.80 | KIF11 (0.46) | KIF11ALDH1A1GABRA1GABRG2GABRB3 | |
| SCHEMBL15840241 | 0.77 | KIF11 (0.50) | KIF11NPC1ALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL17034535 | 0.73 | KIF11 (0.51) | KIF11NPC1ALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL22224112 | 0.73 | KIF11 (0.57) | KIF11NPC1ALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL18858212 | 0.73 | KIF11 (0.40) | KIF11ALDH1A1GABRA1GABRG2GABRB3 | |
| SCHEMBL2603644 | 0.72 | KIF11 (0.42) | KIF11ALDH1A1GABRA1GABRG2GABRB3 | |
| SCHEMBL26485732 | 0.72 | KIF11 (0.56) | KIF11NPC1ALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL21226234 | 0.72 | KIF11 (0.56) | KIF11NPC1ALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL29625605 | 0.72 | KIF11 (0.64) | KIF11ALDH1A1RAB9AGABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015124255-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-08-27 | — | — | WO | disclosed |