Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29339048 | 1.00 | MEN1 (0.44) | MEN1KMT2AEPHX2POLBSMN1; SMN2 | |
| SCHEMBL12195209 | 0.98 | EPHX2 (0.44) | MEN1KMT2AEPHX2POLBSMN1; SMN2 | |
| SCHEMBL5066367 | 0.92 | MEN1 (0.50) | MEN1KMT2AEPHX2POLBSMN1; SMN2 | |
| SCHEMBL22821424 | 0.90 | MEN1 (0.47) | MEN1KMT2AEPHX2POLBSMN1; SMN2 | |
| SCHEMBL20353133 | 0.89 | MEN1 (0.42) | MEN1KMT2AEPHX2POLBSMN1; SMN2 | |
| SCHEMBL25885990 | 0.87 | EPHX2 (0.46) | MEN1KMT2AEPHX2POLBEPHX1 | |
| SCHEMBL25600369 | 0.87 | EPHX2 (0.46) | MEN1KMT2AEPHX2POLBEPHX1 | |
| SCHEMBL19453013 | 0.87 | TSHR (0.42) | MEN1KMT2AEPHX2POLBSMN1; SMN2 | |
| SCHEMBL23729597 | 0.85 | MEN1 (0.42) | MEN1KMT2AEPHX2POLBSMN1; SMN2 | |
| SCHEMBL12673161 | 0.85 | MEN1 (0.45) | MEN1KMT2AEPHX2POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150239928-A1 | CATIONIC STEROIDAL ANTIMICROBIAL COMPOUNDS | BRIGHAM YOUNG UNIVERSITY (US) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239928-A1 | CATIONIC STEROIDAL ANTIMICROBIAL COMPOUNDS | CCL11, SERPINA6, CXCL10 | MEN1 2089/4885KMT2A 4857/4885EPHX2 2514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.