CCL11 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Fondaparinux (SCHEMBL4937)	0.65	1/20
SCHEMBL31087042	0.60	1/20
SCHEMBL8401302	0.50	1/20
Potassium Ion (SCHEMBL17091477)	0.50	1/20
Potassium Ion (SCHEMBL17091479)	0.50	1/20
SCHEMBL18947591	0.49	1/20
SCHEMBL29386492	0.49	1/20
SCHEMBL8401597	0.49	1/20
SCHEMBL15452228	0.48	1/20
SCHEMBL15452257	0.48	1/20
SCHEMBL15452260	0.48	1/20
SCHEMBL15452278	0.48	1/20
SCHEMBL17771212	0.48	1/20
SCHEMBL17771214	0.48	1/20
SCHEMBL18177564	0.48	1/20
SCHEMBL18177566	0.48	1/20
SCHEMBL17000133	0.48	1/20
SCHEMBL18350664	0.48	1/20
SCHEMBL29383445	0.48	1/20
SCHEMBL17167238	0.47	1/20

Clinical trials — most relevant to CCL11 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Study of Azithromycin for Lymphocytic Bronchiolitis/Bronchitis After Lung Transplantation	PHASE4	COMPLETED
Effect of Intravenous Immunglobulin (IVIG) After Myocardial Infarction	PHASE3	COMPLETED
Leronlimab in Patients With Coronavirus Disease 2019 (COVID-19) With Need for Mechanical Ventilation or Extracorporeal Membrane Oxygenation	PHASE3	SUSPENDED
Leronlimab in Moderately Ill Patients With COVID-19 Pneumonia	PHASE3	SUSPENDED
Efficacy of Ibuprofen Chronotherapy in Healing After Surgical Extraction of the Mandibular Third Molar	PHASE2/PHASE3	UNKNOWN
Pilot Efficacy and Safety Study of AQX-1125 in Atopic Dermatitis	PHASE2	COMPLETED
Dose-Ranging Study to Assess the Safety and Efficacy of Melatonin in Outpatients Infected With COVID-19	PHASE2	WITHDRAWN
Anakinra as a Rescue Treatment for Allergic Inflammation	PHASE1/PHASE2	WITHDRAWN
Safety and Efficacy Study of Intravenous Immunoglobulin to Treat Japanese Encephalitis	PHASE2	COMPLETED
Pilot Study to Identify the Mediators and Inflammatory Cell Surface Receptors Involved in Allergic Airway Inflammation	PHASE1	RECRUITING
In Vitro Evaluation of a Novel Drug on Airway Epithelial Cells Obtained From Participants With Severe Asthma	EARLY_PHASE1	COMPLETED
Phenotyping Circulating and Lung Resident Eosinophils in Severe Asthma (P-CLESA)	nan	UNKNOWN
Characterization of Microbiological and Genetic Features in Prostate Cancer and Their Association with Disease Stage	nan	ENROLLING_BY_INVITATION
Evaluation of Eosinophil Phenotype in COPD Patients	nan	UNKNOWN
Investigation of the Efficacy of CARDIO Softgels PLUS Best-standard-of-care in the Recovery of Patients With COVID-19	nan	COMPLETED
Astrocytic Markers and the Pre-ataxic Period of SCA3/MJD - BIGPRO Study Astrocytes	nan	UNKNOWN
A Pilot Feasibility Study of Detection of IL-11 and Other Cytokines in the Exhaled Breath Condensate (EBC) and Blood of Healthy Volunteers	nan	COMPLETED
IL-11 in the Development of Multiple Sclerosis	nan	UNKNOWN
Markers in Exhaled Breath Condensate in Obstructive Sleep Apnoea (OSA) Patients	nan	COMPLETED
Lung-Resident Memory Th2 Cells in Asthma	nan	ACTIVE_NOT_RECRUITING
Regulation of CCL18 by Corticosteroids in Severe Asthma	nan	COMPLETED
Value of Various Chemokines in the Detection and Follow up of RCC	nan	UNKNOWN
Monocyte Chemoattractant Protein-1 in Psoriatic Arthritis Patients	nan	UNKNOWN
To Detect Cryoimmunologic Response Induced by Early Breast Cancer Ultrasound-guided Cryoablation (ICE-study)	nan	COMPLETED
VIDAS® NEPHROCLEAR Reference Interval Study	nan	COMPLETED
Interrelation Between Bronchial Asthma and Smoking	nan	COMPLETED
Genetic Polymorphism Associated With Coronary Heart Disease Susceptibility and Variability of Clopidogrel Response	nan	ACTIVE_NOT_RECRUITING
The Relationship Between Serum Chemokine Ligand 21 (CCL-21) Level and Disease Activity	nan	NOT_YET_RECRUITING
Eosinophil β1 Integrin Activation as a Biomarker for Eosinophilic Esophagitis	nan	COMPLETED
Inflammatory Biomarkers in Psychogenic Non-epileptic Seizure	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a CCL11 binder may also engage these)

Protein	Name	Similarity
Q5RA36	—	0.997	Q5RA36 →
Q8MIT7	—	0.997	Q8MIT7 →
P52203	—	0.995	P52203 →
CCL2	C-C motif chemokine 2	0.992	landscape →
P28291	—	0.991	P28291 →
P80075	—	0.991	P80075 →
P61274	—	0.991	P61274 →
Q9TTQ3	—	0.990	Q9TTQ3 →
P61275	—	0.989	P61275 →
P80098	—	0.987	P80098 →
Q68Y88	—	0.987	Q68Y88 →
Q68AY9	—	0.987	Q68AY9 →
Q9TTQ4	—	0.986	Q9TTQ4 →
P42831	—	0.986	P42831 →
P49873	—	0.985	P49873 →
Q9WUZ6	—	0.982	Q9WUZ6 →
Q9QXY8	—	0.982	Q9QXY8 →
Q9TTS6	—	0.982	Q9TTS6 →
Q99616	—	0.982	Q99616 →
Q09141	—	0.981	Q09141 →
P48298	—	0.976	P48298 →
Q8HYP9	—	0.975	Q8HYP9 →
Q8I021	—	0.974	Q8I021 →
Q03366	—	0.974	Q03366 →
O88430	—	0.973	O88430 →
Q9Y258	—	0.973	Q9Y258 →
Q62401	—	0.972	Q62401 →
Q92583	—	0.972	Q92583 →
P55774	—	0.972	P55774 →
O89093	—	0.971	O89093 →