Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1270636 | 0.86 | ATM (0.39) | ATMLMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL17035909 | 0.86 | ATM (0.39) | ATMLMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL12766925 | 0.83 | LMNA (0.40) | ATMLMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL9618709 | 0.79 | ATM (0.36) | ATMLMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL30668132 | 0.78 | ATM (0.35) | ATMLMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL9465457 | 0.72 | ATM (0.34) | ATMLMNAALDH1A1 | |
| SCHEMBL3189250 | 0.70 | TSHR (0.44) | ATMLMNATSHRHTTSMN1; SMN2 | |
| Potassium Ion SCHEMBL31354832 | 0.68 | ATM (0.35) | ATMLMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL12775686 | 0.67 | KMT2A (0.39) | ATMLMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL3806350 | 0.66 | ERN1 (0.42) | LMNATSHRHTTSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150239796-A1 | ONE POT SYNTHESIS OF 18F LABELEDTRIFLUOROMETHYLATED COMPOUNDS WITH DIFLUORO(IODO)METHANE | UNIVERSITY OF OSLO (NO) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239796-A1 | ONE POT SYNTHESIS OF 18F LABELEDTRIFLUOROMETHYLATED COMPOUNDS WITH DIFLUORO(IODO)METHANE | FLI1, AFF1, CYP2F1 | ATM 2241/4885LMNA 4820/4885TSHR 454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.