SCHEMBL170362

SCHEMBL170362

C=CC(O)c1cccs1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30767689 1.00
SCHEMBL10464880 0.78
SCHEMBL11426273 0.78
SCHEMBL11340407 0.77 CES2 (0.38)
SCHEMBL11340402 0.77 CES2 (0.38)
SCHEMBL10465316 0.75
SCHEMBL4759960 0.74
SCHEMBL1205995 0.74
SCHEMBL9729168 0.74
SCHEMBL1101155 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117645597-A Method for synthesizing key chiral intermediate of duloxetine by asymmetric form hydroamination 江苏恒盛药业有限公司 2024-03-05 CN claimed
CN-114773229-A 1,6 diene compound and preparation method and application thereof 南京工业大学 2022-07-22 CN claimed
WO-2021127642-A1 SELECTIVE VALORIZATION OF BIOMASS SUGARS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-06-24 WO claimed
US-20080260676-A1 HYDROXYCUCURBITURIL DERIVATIVES, THEIR PREPARATION METHODS AND USES POSTECH FOUNDATION (KR) 2008-10-23 US claimed
EP-1463732-A4 HYDROXYCUCURBITURIL DERIVATIVES, THEIR PREPARATION METHODS AND USES POSTECH FOUNDATION (KR) 2005-11-09 EP claimed
US-20050075498-A1 Hydroxycucurbituril derivatives, their preparation methods and uses POSTECH FOUNDATION (KR) 2005-04-07 US claimed
EP-1463732-A1 HYDROXYCUCURBITURIL DERIVATIVES, THEIR PREPARATION METHODS AND USES Postech Foundation (KR) 2004-10-06 EP claimed
WO-2003055888-A1 HYDROXYCUCURBITURIL DERIVATIVES, THEIR PREPARATION METHODS AND USES POSTECH FOUNDATION (KR) 2003-07-10 WO claimed
US-12365927-B2 Engineered ketoreductase polypeptides CODEXIS, INC. (US) 2025-07-22 US disclosed
CN-114773229-B 1,6 Diene compound and preparation method and application thereof 南京工业大学 2024-06-14 CN disclosed
CN-118165002-A Polycyclic compounds and methods of use thereof 桑诺维恩药品公司 2024-06-11 CN disclosed
EP-3252057-B1 MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF SUNOVION PHARMACEUTICALS INC (US) 2024-03-27 EP disclosed
CN-117645597-A Method for synthesizing key chiral intermediate of duloxetine by asymmetric form hydroamination 江苏恒盛药业有限公司 2024-03-05 CN disclosed
CN-117645597-A Method for synthesizing key chiral intermediate of duloxetine by asymmetric form hydroamination 江苏恒盛药业有限公司 2024-03-05 CN disclosed
WO-2003055888-A1 HYDROXYCUCURBITURIL DERIVATIVES, THEIR PREPARATION METHODS AND USES POSTECH FOUNDATION (KR) 2003-07-10 WO disclosed
EP-0707710-A4 SURFACE PLASMON RESONANCE DETECTOR HAVING COLLECTOR FOR ELUTED LIGATE SMITHKLINE BEECHAM CORP (US) 1998-02-25 EP disclosed
US-5561069-A Surface plasmon resonance detector having collector for eluted ligate SMITHKLINE BEECHAM CORPORATION (US) 1996-10-01 US disclosed
EP-0707710-A1 SURFACE PLASMON RESONANCE DETECTOR HAVING COLLECTOR FOR ELUTED LIGATE SMITHKLINE BEECHAM CORPORATION (US) 1996-04-24 EP disclosed
US-5395587-A Surface plasmon resonance detector having collector for eluted ligate SMITHKLINE BEECHAM CORPORATION (US) 1995-03-07 US disclosed
WO-1995002178-A1 SURFACE PLASMON RESONANCE DETECTOR HAVING COLLECTOR FOR ELUTED LIGATE SMITHKLINE BEECHAM CORPORATION (US) 1995-01-19 WO disclosed