Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 5/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17036772 | 0.96 | TDP1 (0.46) | THRBTDP1POLBAPEX1HTT | |
| SCHEMBL17036976 | 0.90 | TDP1 (0.51) | KDM4ETDP1POLBAPEX1HTT | |
| SCHEMBL17037023 | 0.89 | THRB (0.51) | THRBKDM4ETDP1POLBAPEX1 | |
| SCHEMBL17033926 | 0.89 | THRB (0.51) | THRBKDM4ETDP1POLBAPEX1 | |
| SCHEMBL15385973 | 0.85 | TDP1 (0.52) | THRBKDM4ETDP1POLBAPEX1 | |
| SCHEMBL17033933 | 0.85 | TDP1 (0.52) | THRBKDM4ETDP1POLBAPEX1 | |
| SCHEMBL65346 | 0.85 | TDP1 (0.52) | THRBKDM4ETDP1POLBAPEX1 | |
| SCHEMBL17033938 | 0.84 | TDP1 (0.51) | THRBKDM4ETDP1POLBAPEX1 | |
| SCHEMBL28857335 | 0.84 | PPARG (0.47) | THRBTDP1POLBAPEX1HTT | |
| SCHEMBL9561481 | 0.84 | TSHR (0.48) | THRBKDM4ETDP1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015126862-A1 | DENTAL COMPOSITION AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-08-27 | — | — | WO | disclosed |