⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11687828 | 0.97 | ALDH1A1 (1.00) | — | |
| SCHEMBL18010 | 0.97 | — | — | |
| SCHEMBL9616090 | 0.97 | ALDH1A1 (1.00) | — | |
| SCHEMBL1170496 | 0.93 | — | — | |
| SCHEMBL7671122 | 0.86 | — | — | |
| SCHEMBL3400600 | 0.83 | ALDH1A1 (0.67) | — | |
| SCHEMBL17077890 | 0.73 | ALDH1A1 (0.55) | — | |
| SCHEMBL3382967 | 0.73 | — | — | |
| SCHEMBL4136945 | 0.73 | — | — | |
| SCHEMBL947101 | 0.72 | ALDH1A1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11673857-B2 | Preparation method of 1-(4-aminophenyl)cyclopentanecarbonitrile | Zhejiang Rongyao Biotech CO., LTD. (CN) | 2023-06-13 | — | — | US | claimed |
| CN-112441941-B | Preparation method of 1- (4-aminophenyl) cyclopentyl formonitrile | 浙江荣耀生物科技股份有限公司 | 2022-08-02 | — | — | CN | claimed |
| US-20220177420-A1 | PREPARATION METHOD OF 1-(4-AMINOPHENYL)CYCLOPENTANECARBONITRILE | Zhejiang Rongyao Biotech CO., LTD. (CN) | 2022-06-09 | — | — | US | claimed |
| CN-108178724-B | Process for the preparation of compounds | 四川大学 | 2020-09-11 | — | — | CN | claimed |
| EP-0510689-A1 | Hydrocyanation of pentenenitriles using cyanohydrins | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-10-28 | — | — | EP | claimed |
| US-5107012-A | Using an additive to promote dissociation of the cyanohydrin, a nickel complex catalyst and catalyst promoter; slurrying | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-21 | — | — | US | claimed |
| US-20250382312-A1 | BORON CONTAINING PYRAZOLE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF | BORAH INC (US) | 2025-12-18 | — | — | US | disclosed |
| EP-4647434-A1 | MODULATOR FOR PROMOTING BINDING OF BUTYROPHILIN 3A1/2A1 | Unicet Biotech Co., LLC (CN) | 2025-11-12 | — | — | EP | disclosed |
| US-20250313572-A1 | MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE | ABBVIE INC (US) | 2025-10-09 | — | — | US | disclosed |
| US-12404286-B2 | Boron containing pyrazole compounds, compositions comprising them, methods and uses thereof | BORAH, INC. (US) | 2025-09-02 | — | — | US | disclosed |
| US-20250188040-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS INC | 2025-06-12 | — | — | US | disclosed |
| EP-4551555-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | Vividion Therapeutics, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| CN-119677716-A | Pharmaceutical compositions comprising WRN helicase inhibitors | 维维迪恩医疗公司 | 2025-03-21 | — | — | CN | disclosed |
| EP-0731079-A2 | Process for producing a carboxylic acid | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-11 | — | — | EP | disclosed |
| EP-0510689-A1 | Hydrocyanation of pentenenitriles using cyanohydrins | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-10-28 | — | — | EP | disclosed |
| US-5107012-A | Using an additive to promote dissociation of the cyanohydrin, a nickel complex catalyst and catalyst promoter; slurrying | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0187847-A1 | PROCESS FOR THE MANUFACTURE OF 6$g(A)-METHYL STEROIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-07-23 | — | — | EP | disclosed |
| WO-1986000907-A1 | PROCESS FOR THE MANUFACTURE OF 6ALPHA-METHYL STEROIDS | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1986-02-13 | — | — | WO | disclosed |
| US-4482760-A | HYDROGENATING A CYANOHYDRIN | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1984-11-13 | — | — | US | disclosed |
| US-4017539-A | Biguanide compounds and anti-diabetic compositions | BOEHRINGER MANNHEIM G.M.B.H. (DT) | 1977-04-12 | — | — | US | disclosed |