Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20908 | 0.98 | TSHR (0.56) | TSHRCHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL25422044 | 0.98 | TSHR (0.56) | TSHRCHRM5CHRM1CHRM3CHRM2 | |
| Fluoride Ion SCHEMBL1254299 | 0.96 | TSHR (0.54) | TSHRCHRM5CHRM1CHRM3CHRM2 | |
| Water SCHEMBL4899700 | 0.96 | TSHR (0.54) | TSHRCHRM5CHRM1CHRM3CHRM2 | |
| Iodide SCHEMBL1254880 | 0.96 | TSHR (0.54) | TSHRCHRM5CHRM1CHRM3CHRM2 | |
| Hydrochloric Acid SCHEMBL15738807 | 0.96 | TSHR (0.54) | TSHRCHRM5CHRM1CHRM3CHRM2 | |
| Bromide SCHEMBL1254964 | 0.96 | GALR3 (0.57) | TSHRCHRM5CHRM1CHRM3CHRM2 | |
| Hydrochloric Acid SCHEMBL134541 | 0.96 | CHRM5 (0.57) | TSHRCHRM5CHRM1CHRM3CHRM2 | |
| Hydrochloric Acid SCHEMBL28367647 | 0.96 | TSHR (0.54) | TSHRCHRM5CHRM1CHRM3CHRM2 | |
| Hydrochloric Acid SCHEMBL22128460 | 0.94 | TSHR (0.52) | TSHRCHRM5CHRM1CHRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966259-B1 | COPOLYMER CONTAINING ZWITTERIONIC UNITS AND OTHER UNITS, COMPOSITION COMPRISING THE COPOLYMER, AND USE | RHODIA OPERATIONS (FR) | 2012-04-18 | — | — | EP | claimed |
| EP-1967644-A1 | Composite microfibre | Jacobs University Bremen gGmbH (DE) | 2008-09-10 | — | — | EP | claimed |
| US-7098253-B2 | particles of hydrophilic, crosslinked copolymers of N,N'-alkylenebis(meth)acrylamide and a sulfonated N,N'-alkylene bisacrylic amide; chromatographic columns, composite materials, filters; large furface area, ease of manufacture, low material cost, variety of fiber texture, densities | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-08-29 | — | — | US | disclosed |