Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20908 | 0.98 | TSHR (0.56) | TSHRCHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL25422044 | 0.98 | TSHR (0.56) | TSHRCHRM5CHRM1CHRM3CHRM2 | |
| Fluoride Ion SCHEMBL1254299 | 0.96 | TSHR (0.54) | TSHRCHRM5CHRM1CHRM3CHRM2 | |
| Hydrochloric Acid SCHEMBL28367647 | 0.96 | TSHR (0.54) | TSHRCHRM5CHRM1CHRM3CHRM2 | |
| Iodide SCHEMBL1254880 | 0.96 | TSHR (0.54) | TSHRCHRM5CHRM1CHRM3CHRM2 | |
| Bromide SCHEMBL1254964 | 0.96 | GALR3 (0.57) | TSHRCHRM5CHRM1CHRM3CHRM2 | |
| Hydrochloric Acid SCHEMBL15738807 | 0.96 | TSHR (0.54) | TSHRCHRM5CHRM1CHRM3CHRM2 | |
| Hydrochloric Acid SCHEMBL134541 | 0.96 | CHRM5 (0.57) | TSHRCHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL1703727 | 0.96 | TSHR (0.54) | TSHRCHRM5CHRM1CHRM3CHRM2 | |
| Hydrochloric Acid SCHEMBL22128460 | 0.94 | TSHR (0.52) | TSHRCHRM5CHRM1CHRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12618000-B2 | Friction reduction of acidic treatment fluids | HALLIBURTON ENERGY SERVICES, INC. (US) | 2026-05-05 | — | — | US | disclosed |
| US-20260071533-A1 | TREATMENT FLUID SELECTION | HALLIBURTON ENERGY SERVICES, INC. (US) | 2026-03-12 | — | — | US | disclosed |
| US-12247165-B2 | Anti-syneresis agents for fracturing operations | HALLIBURTON ENERGY SERVICES, INC. (US) | 2025-03-11 | — | — | US | disclosed |
| US-20250075122-A1 | ADDITIVES TO PREVENT THERMAL THINNING IN POLYMER GEL SYSTEMS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2025-03-06 | — | — | US | disclosed |
| US-20250051634-A1 | ANTI-SYNERESIS AGENTS FOR FRACTURING OPERATIONS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2025-02-13 | — | — | US | disclosed |
| US-20250051635-A1 | FRICTION REDUCTION OF ACIDIC TREATMENT FLUIDS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2025-02-13 | — | — | US | disclosed |
| WO-2025006003-A1 | FRICTION REDUCTION OF ACIDIC TREATMENT FLUIDS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2025-01-02 | — | — | WO | disclosed |
| US-12139667-B1 | Friction reduction of acidic treatment fluids | HALLIBURTON ENERGY SERVICES, INC. (US) | 2024-11-12 | — | — | US | disclosed |
| WO-2016066633-A1 | NEW FILTRATION PROCESSES | BASF SE (DE) | 2016-05-06 | — | — | WO | disclosed |
| US-9321869-B2 | Cationic polymers | BASF SE (DE) | 2016-04-26 | — | — | US | disclosed |
| US-9057959-B2 | Developer for photosensitive resist material and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2015-06-16 | — | — | US | disclosed |
| US-20150087796-A1 | NEW CATIONIC POLYMERS | BASF SE (DE) | 2015-03-26 | — | — | US | disclosed |
| EP-2836525-A1 | NEW CATIONIC POLYMERS | BASF SE (DE) | 2015-02-18 | — | — | EP | disclosed |
| US-20140377706-A1 | DEVELOPER FOR PHOTOSENSITIVE RESIST MATERIAL AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-12-25 | — | — | US | disclosed |
| CN-104245763-A | New cationic polymers | BASF SE | 2014-12-24 | — | — | CN | disclosed |
| US-20130274369-A1 | NEW CATIONIC POLYMERS | BASF SE (DE) | 2013-10-17 | — | — | US | disclosed |
| WO-2013153004-A1 | NEW CATIONIC POLYMERS | BASF SE (DE) | 2013-10-17 | — | — | WO | disclosed |
| US-20080035344-A1 | DELAYED POLYACRYLAMIDE-CO-ALUMINUM HYDROXYL CHLORIDE GEL | SCHLUMBERGER TECHNOLOGY CORPORATION | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260071533-A1 | TREATMENT FLUID SELECTION | PLG, SOST, CSTB | TSHR 1255/4885CHRM5 3070/4885CHRM1 2745/4885 |
| US-12618000-B2 | Friction reduction of acidic treatment fluids | GFER, FGB, NSF | TSHR 1564/4885CHRM5 4511/4885CHRM1 4594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.