Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | DGAT1 | O75907 | 12/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 9/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20073866 | 0.91 | ALB (0.45) | ALB | |
| SCHEMBL17037280 | 0.82 | ALB (0.45) | ALB | |
| SCHEMBL18359218 | 0.82 | DGAT1 (0.70) | DGAT1FOLH1 | |
| SCHEMBL29293807 | 0.81 | DGAT1 (0.64) | DGAT1FOLH1 | |
| SCHEMBL19248267 | 0.81 | DGAT1 (0.64) | DGAT1FOLH1 | |
| SCHEMBL17706042 | 0.80 | DGAT1 (0.63) | DGAT1FOLH1 | |
| SCHEMBL16666080 | 0.80 | FOLH1 (0.62) | DGAT1FOLH1 | |
| SCHEMBL17706050 | 0.80 | FOLH1 (0.62) | DGAT1FOLH1 | |
| SCHEMBL19248901 | 0.80 | DGAT1 (0.63) | DGAT1FOLH1 | |
| SCHEMBL25681677 | 0.80 | DGAT1 (0.62) | DGAT1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180104354-A1 | CHIMERIC ANTIGEN RECEPTOR T CELL SWITCHES AND USES THEREOF | THE SCRIPPS RESEARCH INSTITUTE | 2018-04-19 | — | — | US | disclosed |
| US-20150238631-A1 | CHIMERIC ANTIGEN RECEPTOR T CELL SWITCHES AND USES THEREOF | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180104354-A1 | CHIMERIC ANTIGEN RECEPTOR T CELL SWITCHES AND USES THEREOF | ICOS, HAVCR2, CD2 | ALB 3148/4885DGAT1 2674/4885FOLH1 1953/4885 |
| US-20150238631-A1 | CHIMERIC ANTIGEN RECEPTOR T CELL SWITCHES AND USES THEREOF | ICOS, HAVCR2, CD2 | ALB 3148/4885DGAT1 2674/4885FOLH1 1953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.