Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHAT | P28329 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17037919 | 0.83 | CHAT (0.35) | CHATMEN1KMT2APABPC1RAB9A | |
| SCHEMBL17037904 | 0.81 | CHAT (0.35) | CHATMEN1KMT2APABPC1RAB9A | |
| SCHEMBL17040347 | 0.80 | MGAM (0.35) | MEN1KMT2ARAB9A | |
| SCHEMBL17037929 | 0.80 | CHAT (0.35) | CHATMEN1KMT2APABPC1RAB9A | |
| SCHEMBL17037924 | 0.79 | CHAT (0.35) | CHATMEN1KMT2APABPC1RAB9A | |
| SCHEMBL17037903 | 0.79 | CHAT (0.35) | CHATMEN1KMT2APABPC1RAB9A | |
| SCHEMBL17037921 | 0.79 | CHAT (0.35) | CHATMEN1KMT2APABPC1RAB9A | |
| SCHEMBL17037890 | 0.78 | KDM4E (0.36) | MEN1KMT2A | |
| SCHEMBL17037905 | 0.78 | CHAT (0.34) | CHATMEN1KMT2APABPC1RAB9A | |
| SCHEMBL17037911 | 0.77 | CHAT (0.35) | CHATMEN1KMT2APABPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9547009-B2 | Benzocyclooctyne compounds and uses thereof | ACADEMIA SINICA (TW) | 2017-01-17 | — | — | US | disclosed |
| US-20150241439-A1 | BENZOCYCLOOCTYNE COMPOUNDS AND USES THEREOF | ACADEMIA SINICA (TW) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150241439-A1 | BENZOCYCLOOCTYNE COMPOUNDS AND USES THEREOF | AADAC, TBCA, SPG11 | CHAT 1860/4885MEN1 3600/4885KMT2A 4699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.