Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.39 |
| ▸ | NQO2 | P16083 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15839223 | 0.89 | STING1 (0.48) | NPC1RAB9AGAAMAPK1ALOX15 | |
| SCHEMBL13735279 | 0.80 | NQO2 (0.46) | NPC1RAB9AGAAALOX15ATM | |
| SCHEMBL15949819 | 0.79 | STING1 (0.43) | NPC1RAB9AGAAMAPK1ALOX15 | |
| SCHEMBL9310828 | 0.78 | GAA (0.66) | NPC1RAB9AGAAALOX15ATM | |
| SCHEMBL11685051 | 0.76 | CYP3A4 (0.68) | NPC1RAB9AGAAALOX15ATM | |
| SCHEMBL13164798 | 0.76 | ALOX15 (0.43) | NPC1RAB9AGAAALOX15ATM | |
| SCHEMBL10271768 | 0.73 | NPC1 (0.69) | NPC1RAB9AGAAMAPK1ALOX15 | |
| SCHEMBL7542512 | 0.73 | CYP1A2 (0.59) | NPC1RAB9AGAAMAPTSMN1; SMN2 | |
| SCHEMBL30917348 | 0.73 | NPC1 (0.50) | NPC1RAB9AMAPK1ALOX15NQO2 | |
| SCHEMBL200838 | 0.73 | NPC1 (0.50) | NPC1RAB9AMAPK1ALOX15NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150239878-A1 | Novel Compounds for Imaging Tau Proteins That Accumulate In Brain | NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239878-A1 | Novel Compounds for Imaging Tau Proteins That Accumulate In Brain | MAPT, FABP7, HTT | NPC1 1994/4885RAB9A 1040/4885GAA 4201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.