SCHEMBL17038451

SCHEMBL17038451

c1ccc2c(c1)-c1ccccc1C21c2ccccc2-c2ccc(-n3c4ccccc4c4ccc(-n5c6ccccc6c6ccccc65)cc43)cc21

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.42
ATM Q13315 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
PDK2 Q15119 7/20 0.34
DUSP3 P51452 1/20 0.33
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
OPRK1 P41145 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12171156 0.95 KDM4E (0.46) KDM4EATML3MBTL1PDK2DUSP3
SCHEMBL12292088 0.95 KDM4E (0.46) KDM4EATML3MBTL1PDK2DUSP3
SCHEMBL390193 0.95 KDM4E (0.46) KDM4EATML3MBTL1PDK2DUSP3
SCHEMBL29664894 0.95 KDM4E (0.46) KDM4EATML3MBTL1PDK2DUSP3
SCHEMBL30077228 0.95 KDM4E (0.46) KDM4EATML3MBTL1PDK2DUSP3
SCHEMBL24667553 0.92 KDM4E (0.41) KDM4EATML3MBTL1PDK2DUSP3
SCHEMBL17854687 0.91 KDM4E (0.42) KDM4EATML3MBTL1PDK2DUSP3
SCHEMBL17854692 0.91 KDM4E (0.42) KDM4EATML3MBTL1PDK2DUSP3
SCHEMBL601646 0.91 KDM4E (0.50) KDM4EATML3MBTL1PDK2DUSP3
SCHEMBL30293940 0.91 KDM4E (0.50) KDM4EATML3MBTL1PDK2DUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10707423-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-07-07 US disclosed
US-20150243894-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2015-08-27 US disclosed
US-20150243894-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2015-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10707423-B2 Organic electroluminescent materials and devices OCIAD1, OXA1L, SLCO2B1 KDM4E 3237/4885ATM 3925/4885L3MBTL1 517/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.