SCHEMBL601646

SCHEMBL601646

c1ccc2c(c1)c1ccccc1n2-c1ccc2c(c1)C1(c3cc(-n4c5ccccc5c5ccccc54)ccc3-2)c2cc(-n3c4ccccc4c4ccccc43)ccc2-c2ccc(-n3c4ccccc4c4ccccc43)cc21

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.50
ATM Q13315 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
GPR3 P46089 1/20 0.34
DUSP3 P51452 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
POLB P06746 1/20 0.33
PTPN1 P18031 2/20 0.33
PDK2 Q15119 7/20 0.33
ALDH1A1 P00352 1/20 0.33
HDAC4 P56524 1/20 0.32
EDNRB P24530 1/20 0.30
EDNRA P25101 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30293940 1.00 KDM4E (0.50) KDM4EATML3MBTL1GPR3DUSP3
SCHEMBL12171156 0.95 KDM4E (0.46) KDM4EATML3MBTL1GPR3DUSP3
SCHEMBL12292088 0.95 KDM4E (0.46) KDM4EATML3MBTL1GPR3DUSP3
SCHEMBL29664894 0.95 KDM4E (0.46) KDM4EATML3MBTL1GPR3DUSP3
SCHEMBL30077228 0.95 KDM4E (0.46) KDM4EATML3MBTL1GPR3DUSP3
SCHEMBL390193 0.95 KDM4E (0.46) KDM4EATML3MBTL1GPR3DUSP3
SCHEMBL21008867 0.93 KDM4E (0.44) KDM4EATML3MBTL1GPR3DUSP3
SCHEMBL17854687 0.91 KDM4E (0.42) KDM4EATML3MBTL1DUSP3PDK2
SCHEMBL21364086 0.91 KDM4E (0.42) KDM4EATML3MBTL1POLBPDK2
SCHEMBL17038451 0.91 KDM4E (0.42) KDM4EATML3MBTL1DUSP3PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 467 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2117063-B1 ORGANIC ELECTROLUMINESCENCE ELEMENT DAINIPPON PRINTING CO LTD (JP) 2012-09-26 EP claimed
US-20100096622-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT DAI NIPPON PRINTING CO., LTD. (JP) 2010-04-22 US claimed
EP-2117063-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT Dainippon Printing Co., Ltd. (JP) 2009-11-11 EP claimed
US-12048175-B2 Organic electroluminescent device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2024-07-23 US disclosed
US-12029116-B2 Composition of matter for use in organic light-emitting diodes KYULUX, INC. (JP) 2024-07-02 US disclosed
US-12029116-B2 Composition of matter for use in organic light-emitting diodes KYULUX, INC. (JP) 2024-07-02 US disclosed
US-20240190908-A1 BLUE PHOSPHORESCENT EMITTERS EMPLOYING FUNCTIONALIZED IMIDAZOPHENTHRIDINE AND ANALOGUES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2024-06-13 US disclosed
US-20240191132-A1 METAL ASSISTED DELAYED FLUORESCENT EMITTERS FOR ORGANIC LIGHT-EMITTING DIODES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2024-06-13 US disclosed
US-11945985-B2 Metal assisted delayed fluorescent emitters for organic light-emitting diodes ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2024-04-02 US disclosed
US-20240032422-A1 LIGHT-EMITTING MATERIAL, COMPOUND, LONG-PERSISTENT PHOSPHOR AND LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2024-01-25 US disclosed
US-11878988-B2 Blue phosphorescent emitters employing functionalized imidazophenthridine and analogues ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2024-01-23 US disclosed
EP-1641894-A1 NOVEL MATERIALS FOR ELECTROLUMINESCENCE Covion Organic Semiconductors GmbH (DE) 2006-04-05 EP disclosed
WO-2004113468-A1 NOVEL MATERIALS FOR ELECTROLUMINESCENCE COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2004-12-29 WO disclosed
US-6822094-B2 AMORPHOUS SPIROBIFLUORENE COMPOUND USED IN A PHOTOVOLTIC CELL AS CHARGE TRANSPORTING MATERIAL AVENTIS RESEARCH & TECHNOLOGIES, GMBH & CO. KG (DE) 2004-11-23 US disclosed
US-20040043197-A1 Low dielectric constant insulating material, and electronic part FUJITSU LIMITED (JP) 2004-03-04 US disclosed
US-6603150-B2 An organic light-emitting device includes a substrate, an anode, a cathode, disposed between the anode and the cathode is an electroluminescent medium including, in sequence: a hole- transporting layer an interface layer; a light-emitting EASTMAN KODAK COMPANY 2003-08-05 US disclosed
US-20030111107-A1 Spiro compounds and their use MERCK OLED MATERIALS GMBH (DE) 2003-06-19 US disclosed
US-20030075720-A1 Organic light-emitting diode having an interface layer between the hole-transporting layer and the light-emitting layer EASTMAN KODAK COMPANY 2003-04-24 US disclosed
EP-1298737-A2 Organic light emitting diode having an interface layer between the hole-transporting layer and the light-emitting layer EASTMAN KODAK COMPANY (US) 2003-04-02 EP disclosed
EP-0968175-B1 SPIRO COMPOUNDS AND THE USE THEREOF CELANESE VENTURES GMBH (DE) 2001-12-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11878988-B2 Blue phosphorescent emitters employing functionalized imidazophenthridine and analogues EML4, TYR, TYMP KDM4E 1356/4885ATM 3953/4885L3MBTL1 58/4885
US-20240032422-A1 LIGHT-EMITTING MATERIAL, COMPOUND, LONG-PERSISTENT PHOSPHOR AND LIGHT-EMITTING ELEMENT NR2E3, CRY1, ESR1 KDM4E 4118/4885ATM 735/4885L3MBTL1 283/4885
US-12029116-B2 Composition of matter for use in organic light-emitting diodes OPRD1, DRD1, DRD3 KDM4E 3197/4885ATM 3673/4885L3MBTL1 442/4885
US-20030111107-A1 Spiro compounds and their use PKD1, PKD2, REN KDM4E 3990/4885ATM 2636/4885L3MBTL1 2342/4885
US-20240190908-A1 BLUE PHOSPHORESCENT EMITTERS EMPLOYING FUNCTIONALIZED IMIDAZOPHENTHRIDINE AND ANALOGUES EML4, TYR, TYMP KDM4E 1356/4885ATM 3953/4885L3MBTL1 58/4885
US-11945985-B2 Metal assisted delayed fluorescent emitters for organic light-emitting diodes ETFA, CACNA1F, CYP4F2 KDM4E 4218/4885ATM 3283/4885L3MBTL1 1531/4885
US-20240191132-A1 METAL ASSISTED DELAYED FLUORESCENT EMITTERS FOR ORGANIC LIGHT-EMITTING DIODES ETFA, CACNA1F, CYP4F2 KDM4E 4218/4885ATM 3283/4885L3MBTL1 1531/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.