⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258147 | 0.84 | — | — | |
| SCHEMBL258235 | 0.81 | CYP2D6 (0.32) | — | |
| SCHEMBL4330824 | 0.75 | — | — | |
| SCHEMBL4315563 | 0.75 | — | — | |
| SCHEMBL8447215 | 0.67 | — | — | |
| SCHEMBL1032428 | 0.58 | — | — | |
| SCHEMBL7528242 | 0.53 | — | — | |
| SCHEMBL2308676 | 0.53 | ALDH1A1 (0.30) | — | |
| SCHEMBL12180002 | 0.52 | — | — | |
| SCHEMBL16144920 | 0.49 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1656 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117425660-A | Aromatic heterocyclic compound, intermediate thereof, pharmaceutical composition and application | 上海翊石医药科技有限公司 | 2024-01-19 | — | — | CN | claimed |
| CN-116715700-A | CD73 inhibitor, preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2023-09-08 | — | — | CN | claimed |
| US-11731981-B2 | CCR2 receptor antagonists and uses thereof | CENTREXION THERAPEUTICS CORPORATION (US) | 2023-08-22 | — | — | US | claimed |
| CN-116535423-A | Compound for inhibiting/inducing degradation of EGFR kinase, and pharmaceutical composition and application thereof | 武汉誉祥医药科技有限公司 | 2023-08-04 | — | — | CN | claimed |
| WO-2023141852-A1 | CDK2 INHIBITORS, PREPARATION METHOD THEREFOR AND USE THEREOF | 益方生物科技(上海)股份有限公司 | 2023-08-03 | — | — | WO | claimed |
| US-20230101747-A1 | CYCLIC COMPOUNDS AND METHODS OF USING SAME | SCHRÖDINGER, INC. | 2023-03-30 | — | — | US | claimed |
| CN-115427407-A | Novel N-heterocyclic BET bromodomain inhibitor, preparation method and medical application thereof | 成都苑东生物制药股份有限公司 | 2022-12-02 | — | — | CN | claimed |
| CN-115141202-A | Pyrimidopyrazinone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-04 | — | — | CN | claimed |
| US-20220002310-A1 | CCR2 RECEPTOR ANTAGONISTS AND USES THEREOF | ANKURA TRUST COMPANY, LLC, AS ADMINISTRATIVE AND COLLATERAL AGENT | 2022-01-06 | — | — | US | claimed |
| CN-113366008-A | CD73 inhibitor, preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2021-09-07 | — | — | CN | claimed |
| EP-1556052-A4 | MITOTIC KINESIN INHIBITORS | MERCK & CO INC (US) | 2006-11-02 | — | — | EP | claimed |
| US-7098350-B2 | E2,E4,Z8-undecatrienoic acid and ester and carboxamide derivatives thereof, organoleptic uses thereof and processes for preparing same | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2006-08-29 | — | — | US | claimed |
| EP-1556052-A2 | MITOTIC KINESIN INHIBITORS | Merck & Co., Inc. (US) | 2005-07-27 | — | — | EP | claimed |
| EP-1496042-A2 | E2, E4,Z8-Undecatrienoic acid and ester and carboxamide derivatives thereof, organoleptic uses thereof and processes for preparing same | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2005-01-12 | — | — | EP | claimed |
| CN-1564660-A | Selective herbicides based on substituted cyclic ketoenols and safeners | BAYER CROPSCIENCE AG (DE) | 2005-01-12 | — | — | CN | claimed |
| CN-1555221-A | Selective herbicides based on substituted thien-3-yl-sulfonylamino(thio)carbonyl-triazolin(thi)ones and safeners | �ݶ�ũ�����ѧ�ɷݹ�˾ | 2004-12-15 | — | — | CN | claimed |
| WO-2004037171-A2 | MITOTIC KINESIN INHIBITORS | MERCK & CO., INC. (US) | 2004-05-06 | — | — | WO | claimed |
| EP-0010317-B1 | 6-, 1- AND 2-SUBSTITUTED-1-CARBAPEN-2-EM-3-CARBOXYLIC ACIDS, PROCESSES FOR THE PREPARATION OF SUCH COMPOUNDS AND PHARMACEUTICAL COMPOSITION COMPRISING SUCH COMPOUNDS | MERCK & CO. INC. (US) | 1983-12-21 | — | — | EP | claimed |
| US-4372965-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1983-02-08 | — | — | US | claimed |
| EP-0010317-A1 | 6-, 1- and 2-substituted-1-carbapen-2-em-3-carboxylic acids, processes for the preparation of such compounds and pharmaceutical composition comprising such compounds | MERCK & CO. INC. (US) | 1980-04-30 | — | — | EP | claimed |