Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 5/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15427687 | 0.83 | ALDH1A1 (0.56) | NQO2ALDH1A1GAAMAPK1MEN1 | |
| SCHEMBL505830 | 0.81 | KMT2A (0.40) | ALDH1A1GAAMEN1KMT2AF2 | |
| SCHEMBL6776351 | 0.81 | ALDH1A1 (0.47) | NQO2ALDH1A1GAAMAPK1MEN1 | |
| SCHEMBL17039629 | 0.81 | NQO2 (0.51) | NQO2ALDH1A1GAAMAPK1MEN1 | |
| Ethyl Propionate SCHEMBL28977492 | 0.80 | NPC1 (0.41) | ALDH1A1GAAMAPK1MEN1KMT2A | |
| SCHEMBL17546280 | 0.79 | ALDH1A1 (0.58) | NQO2ALDH1A1GAAMAPK1MEN1 | |
| SCHEMBL17052609 | 0.78 | NQO2 (0.42) | NQO2ALDH1A1GAAMAPK1MEN1 | |
| SCHEMBL15562472 | 0.77 | NQO2 (0.56) | NQO2ALDH1A1GAAMAPK1MEN1 | |
| SCHEMBL15562470 | 0.77 | NQO2 (0.57) | NQO2ALDH1A1GAAMAPK1MEN1 | |
| SCHEMBL1269634 | 0.77 | NQO2 (0.54) | NQO2ALDH1A1GAAMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116239572-A | Preparation method of dabigatran etexilate intermediate | 宿迁盛基医药科技有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-110128407-B | Preparation method of dabigatran etexilate key intermediate | 连云港恒运药业有限公司 | 2022-04-01 | — | — | CN | disclosed |
| WO-2015124764-A1 | SYNTHESIS PROCESS OF DABIGATRAN ETEXILATE MESYLATE, INTERMEDIATES OF THE PROCESS AND NOVEL POLYMORPH OF DABIGATRAN ETEXILATE | ERREGIERRE S.P.A. (IT) | 2015-08-27 | — | — | WO | disclosed |