Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL898392 | 1.00 | ALK (0.44) | ALK | |
| SCHEMBL20004790 | 0.84 | ALK (0.55) | ALK | |
| SCHEMBL20356882 | 0.84 | ALK (0.44) | ALK | |
| SCHEMBL898393 | 0.83 | ALK (0.48) | ALK | |
| SCHEMBL1704002 | 0.83 | ALK (0.48) | ALK | |
| SCHEMBL19988197 | 0.82 | ALK (0.43) | ALK | |
| SCHEMBL20356890 | 0.82 | ALK (0.43) | ALK | |
| SCHEMBL898394 | 0.81 | ALK (0.46) | ALK | |
| SCHEMBL897843 | 0.76 | ALK (0.57) | ALK | |
| SCHEMBL897782 | 0.76 | ALK (0.69) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2441753-A1 | TETRACYCLIC COMPOUND | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-04-18 | — | — | EP | disclosed |