SCHEMBL170402

SCHEMBL170402

Nc1ccc(/C=C\c2ccc(N)cc2S(=O)(=O)O)c(S(=O)(=O)O)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAD1 O60671 1/20 0.51
P2RY6 Q15077 1/20 0.51
RAPGEF4 Q8WZA2 1/20 0.50
ENPP2 Q13822 1/20 0.47
ALDH1A1 P00352 6/20 0.47
TDP1 Q9NUW8 4/20 0.47
RECQL P46063 3/20 0.47
CASP6 P55212 3/20 0.47
KDM4E B2RXH2 2/20 0.47
POLB P06746 2/20 0.47
GAA P10253 2/20 0.47
MAPT P10636 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
NSD2 O96028 2/20 0.47
APEX1 P27695 1/20 0.47
APOBEC3A P31941 1/20 0.47
APOBEC3G Q9HC16 1/20 0.47
SENP2 Q9HC62 5/20 0.47
SENP1 Q9P0U3 5/20 0.47
SENP3 Q9H4L4 4/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38872 1.00 RAD1 (0.51) RAD1P2RY6RAPGEF4ENPP2ALDH1A1
SCHEMBL29397316 1.00 RAD1 (0.51) RAD1P2RY6RAPGEF4ENPP2ALDH1A1
SCHEMBL38871 1.00 RAD1 (0.51) RAD1P2RY6RAPGEF4ENPP2ALDH1A1
SCHEMBL30616157 1.00 RAD1 (0.51) RAD1P2RY6RAPGEF4ENPP2ALDH1A1
SCHEMBL5858437 0.98 RAD1 (0.50) RAD1P2RY6RAPGEF4ENPP2ALDH1A1
SCHEMBL602305 0.98 RAD1 (0.50) RAD1P2RY6RAPGEF4ENPP2ALDH1A1
SCHEMBL8492598 0.98 RAD1 (0.50) RAD1P2RY6RAPGEF4ENPP2ALDH1A1
SCHEMBL602303 0.98 RAD1 (0.50) RAD1P2RY6RAPGEF4ENPP2ALDH1A1
Ammonia Solution, Strong SCHEMBL7549518 0.98 RAD1 (0.50) RAD1P2RY6RAPGEF4ENPP2ALDH1A1
SCHEMBL6397275 0.98 RAD1 (0.50) RAD1P2RY6RAPGEF4ENPP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2633088-B1 NON METAL TANNING STAHL INT B V (NL) 2018-09-12 EP disclosed
EP-2633086-B1 NON-METAL TANNING PROCESS STAHL INT B V (NL) 2017-08-16 EP disclosed
EP-2633089-B1 NON METAL TANNING STAHL INT B V (NL) 2017-03-15 EP disclosed
EP-2638181-B1 NON METAL TANNING STAHL INT B V (NL) 2017-02-22 EP disclosed
EP-2638179-B1 NON METAL TANNING STAHL INT BV (NL) 2014-11-26 EP disclosed
EP-2638180-B1 NON METAL TANNING STAHL INT BV (NL) 2014-11-26 EP disclosed
EP-2633087-B1 NON-METAL TANNING PROCESS STAHL INT BV (NL) 2014-09-17 EP disclosed
US-8808398-B2 Non metal tanning STAHL INTERNATIONAL B.V. (NL) 2014-08-19 US disclosed
US-8801804-B2 Non-metal tanning process STAHL INTERNATIONAL B.V. (NL) 2014-08-12 US disclosed
US-8795389-B2 Non metal tanning STAHL INTERNATIONAL B.V. (NL) 2014-08-05 US disclosed
EP-2633086-A1 NON-METAL TANNING PROCESS Clariant Finance (BVI) Limited (VG) 2013-09-04 EP disclosed
US-20130219634-A1 Non Metal Tanning CLARIANT FINANCE (BVI) LIMITED (VG) 2013-08-29 US disclosed
US-20130205516-A1 Non Metal Tanning CLARIANT FINANCE (BVI) LIMITED (VG) 2013-08-15 US disclosed
US-20130198974-A1 Non-Metal Tanning Process CLARIANT FINANCE (BVI) LIMITED (VG) 2013-08-08 US disclosed
EP-2430197-B1 TANNING PROCESS AND TANNING COMPOSITION CLARIANT FINANCE BVI LTD (VG) 2013-01-16 EP disclosed
WO-2012062413-A1 NON METAL TANNING CLARIANT INTERNATIONAL LTD (CH) 2012-05-18 WO disclosed
WO-2012055482-A1 NON-METAL TANNING PROCESS CLARIANT INTERNATIONAL LTD (CH) 2012-05-03 WO disclosed
EP-2430197-A1 TANNING PROCESS AND TANNING COMPOSITION Clariant Finance (BVI) Limited (VG) 2012-03-21 EP disclosed
US-20120058357-A1 Tanning Process and Tanning Composition CLARIANT FINANCE (BVI) LIMITED (VG) 2012-03-08 US disclosed
WO-2010130311-A1 TANNING PROCESS AND TANNING COMPOSITION CLARIANT INTERNATIONAL LTD (CH) 2010-11-18 WO disclosed