SCHEMBL602303

SCHEMBL602303

Nc1ccc(/C=C/c2ccc(N)cc2S(=O)(=O)O)c(S(=O)(=O)O)c1.[NaH].[NaH]

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAD1 O60671 1/20 0.50
P2RY6 Q15077 1/20 0.50
RAPGEF4 Q8WZA2 1/20 0.49
ENPP2 Q13822 1/20 0.46
ALDH1A1 P00352 6/20 0.46
TDP1 Q9NUW8 4/20 0.46
RECQL P46063 3/20 0.46
KDM4E B2RXH2 2/20 0.46
POLB P06746 2/20 0.46
GAA P10253 2/20 0.46
MAPT P10636 2/20 0.46
CASP6 P55212 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
NSD2 O96028 1/20 0.46
APEX1 P27695 1/20 0.46
APOBEC3A P31941 1/20 0.46
APOBEC3G Q9HC16 1/20 0.46
SENP2 Q9HC62 6/20 0.46
SENP1 Q9P0U3 5/20 0.46
SENP3 Q9H4L4 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5858431 1.00 RAD1 (0.50) RAD1P2RY6RAPGEF4ENPP2ALDH1A1
SCHEMBL5858437 1.00 RAD1 (0.50) RAD1P2RY6RAPGEF4ENPP2ALDH1A1
SCHEMBL6397275 1.00 RAD1 (0.50) RAD1P2RY6RAPGEF4ENPP2ALDH1A1
SCHEMBL38871 0.98 RAD1 (0.51) RAD1P2RY6RAPGEF4ENPP2ALDH1A1
SCHEMBL170402 0.98 RAD1 (0.51) RAD1P2RY6RAPGEF4ENPP2ALDH1A1
SCHEMBL38872 0.98 RAD1 (0.51) RAD1P2RY6RAPGEF4ENPP2ALDH1A1
SCHEMBL30616157 0.98 RAD1 (0.51) RAD1P2RY6RAPGEF4ENPP2ALDH1A1
SCHEMBL29397316 0.98 RAD1 (0.51) RAD1P2RY6RAPGEF4ENPP2ALDH1A1
Ammonia Solution, Strong SCHEMBL7549518 0.96 RAD1 (0.50) RAD1P2RY6RAPGEF4ENPP2ALDH1A1
SCHEMBL8492598 0.96 RAD1 (0.50) RAD1P2RY6RAPGEF4ENPP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017072788-A1 IMPROVED OPTICAL BRIGHTENING AGENT FOR DETERGENT FORMULATIONS AND A PROCESS FOR PREPARING THE SAME DEEPAK NITRITE LIMITED (IN) 2017-05-04 WO claimed
US-4299910-A AMINO AND/OR NITRO-SUBSTITUTED STILBENE DISULFONIC ACIDS RCA CORPORATION (US) 1981-11-10 US claimed
WO-2017072788-A1 IMPROVED OPTICAL BRIGHTENING AGENT FOR DETERGENT FORMULATIONS AND A PROCESS FOR PREPARING THE SAME DEEPAK NITRITE LIMITED (IN) 2017-05-04 WO disclosed
EP-2478153-B1 DISULFO-TYPE FLUORESCENT WHITENING AGENT COMPOSITIONS BLANKOPHOR GMBH & CO KG (DE) 2014-12-17 EP disclosed
EP-0884312-B2 Triazinylaminostilbene compounds BASF SE (DE) 2014-11-26 EP disclosed
US-8785362-B2 Triazine derivative dye transfer inhibitors, washing products containing the same and uses therefor HENKEL AG & CO. KGAA (DE) 2014-07-22 US disclosed
US-8696868-B2 Disulfo-type fluorescent whitening agent compositions BLANKOPHOR GMBH & CO. KG (DE) 2014-04-15 US disclosed
WO-2012171876-A1 USE OF FLUORESCENT WHITENING AGENT COMPOSITIONS FOR WHITENING PAPER BLANKOPHOR GMBH & CO. KG (DE) 2012-12-20 WO disclosed
EP-2535455-A1 Use of fluorescent whitening agent compositions for whitening paper Blankophor GmbH & Co. KG (DE) 2012-12-19 EP disclosed
US-8263541-B2 comprising a dye transfer inhibitor selected from triazine derivatives such as N,N'-bis-[2-chloro-4(sulfonaphth-1-yl-amino)-triazin-6-yl]-1,2-diaminoethane, optionally mixed with polymers and an aqueous solution of surfactants; colorfastness HENKEL AG & CO. KGAA (DE) 2012-09-11 US disclosed
US-20120199302-A1 DISULFO-TYPE FLUORESCENT WHITENING AGENT COMPOSITIONS BLANKOPHOR GMBH & CO. KG (DE) 2012-08-09 US disclosed
US-6153122-A Triazinylaminostilbene compounds CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-11-28 US disclosed
US-6121444-A Process for preparing substituted 4,4'-diaminostilbene-2,2'-disulphonic acid salts BAYER AKTIENGESELLSCHAFT (DE) 2000-09-19 US disclosed
US-6045586-A IMPROVING THE SUN PROTECTION FACTOR (SPF) OF TEXTILE FIBRE BY TREATING WITH 1,3,5-TRIAZINE DERIVATIVES OF GIVEN FORMULA CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-04-04 US disclosed
EP-0884312-A1 Triazinylaminostilbene compounds Ciba SC Holding AG (CH) 1998-12-16 EP disclosed
US-5741905-A Triazine ultraviolet absorbers useful for improving the sun protection factor of textiles CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-04-21 US disclosed
US-5681832-A FOR TREATMENT OF VIRAL DISEASES BY SUPPRESSING REPLICATION OF RETROVIRUSES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1997-10-28 US disclosed
WO-1996025399-A1 NOVEL AROYLANILINE DERIVATIVES, COMPOSITIONS AND USES THEREOF IN THE TREATMENT OF VIRAL INFECTIONS THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1996-08-22 WO disclosed
EP-0693483-A1 Compounds having ultra-violet absorption properties CIBA-GEIGY AG (CH) 1996-01-24 EP disclosed
US-4299910-A AMINO AND/OR NITRO-SUBSTITUTED STILBENE DISULFONIC ACIDS RCA CORPORATION (US) 1981-11-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120199302-A1 DISULFO-TYPE FLUORESCENT WHITENING AGENT COMPOSITIONS ARSA, DSG1, DDO RAD1 4386/4885P2RY6 886/4885RAPGEF4 4490/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.