Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 15/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 14/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.42 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16976840 | 0.82 | CDK1 (0.44) | HSP90AB1HSP90AA1HDAC6HDAC1HDAC4 | |
| SCHEMBL6510998 | 0.80 | CDK1 (0.58) | HSP90AB1HSP90AA1HSP90B1 | |
| SCHEMBL9663203 | 0.79 | HDAC6 (0.47) | HSP90AB1HSP90AA1HDAC6HDAC1HDAC4 | |
| SCHEMBL764036 | 0.79 | CDK1 (0.59) | HSP90AB1HSP90AA1HSP90B1TRAP1 | |
| SCHEMBL24474430 | 0.79 | HSP90AB1 (0.46) | HSP90AB1HSP90AA1HDAC6HDAC1HDAC4 | |
| SCHEMBL27531530 | 0.77 | CDK2 (0.39) | HDAC6HDAC1HDAC4 | |
| SCHEMBL27220347 | 0.77 | CDK1 (0.42) | HSP90AB1HSP90AA1 | |
| SCHEMBL3272905 | 0.77 | HDAC6 (0.48) | HSP90AB1HSP90AA1HDAC6HDAC1HDAC4 | |
| SCHEMBL15789757 | 0.77 | CDK1 (0.50) | HSP90AB1HSP90AA1HDAC6HDAC1HDAC4 | |
| SCHEMBL8080153 | 0.77 | HSP90AB1 (0.47) | HSP90AB1HSP90AA1HDAC6HDAC1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015125782-A1 | METHOD FOR PRODUCING THIOLANE-SKELETON GLYCOCONJUGATE, AND THIOLANE-SKELETON GLYCOCONJUGATE | 富士フイルム株式会社 | 2015-08-27 | — | — | WO | disclosed |
| WO-2015125781-A1 | METHOD FOR PRODUCTING THIOLANE SKELETON-TYPE GLYCOCONJUGATE, AND THIOLANE SKELETON-TYPE GLYCOCONJUGATE | 富士フイルム株式会社 | 2015-08-27 | — | — | WO | disclosed |