Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 18/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 17/20 | 0.47 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.42 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3964706 | 0.82 | CDK1 (0.57) | HSP90AB1HSP90AA1HSP90B1 | |
| SCHEMBL764036 | 0.79 | CDK1 (0.59) | HSP90AB1HSP90AA1HSP90B1TRAP1 | |
| SCHEMBL17040218 | 0.77 | HSP90AB1 (0.47) | HSP90AB1HSP90AA1HSP90B1TRAP1HDAC6 | |
| SCHEMBL31036942 | 0.76 | HSP90AA1 (0.30) | HSP90AB1HSP90AA1 | |
| SCHEMBL10585228 | 0.76 | ACHE (0.35) | — | |
| SCHEMBL24474430 | 0.75 | HSP90AB1 (0.46) | HSP90AB1HSP90AA1HSP90B1TRAP1HDAC6 | |
| SCHEMBL9663203 | 0.75 | HDAC6 (0.47) | HSP90AB1HSP90AA1HDAC6HDAC4HDAC1 | |
| SCHEMBL756290 | 0.75 | CDK2 (0.71) | HSP90AB1HSP90AA1HDAC1 | |
| SCHEMBL27854926 | 0.75 | CDK1 (0.71) | HSP90AB1HSP90AA1HSP90B1TRAP1HDAC6 | |
| SCHEMBL27439485 | 0.75 | HSP90AB1 (0.46) | HSP90AB1HSP90AA1HSP90B1TRAP1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6034087-A | VIRICIDE AGAINST HEPATITIS B | CHONG KUN DANG CORP. (KR) | 2000-03-07 | — | — | US | disclosed |
| EP-0869953-A1 | NUCLEOSIDE DERIVATIVES AND PROCESS FOR PREPARING THEREOF | CHONG KUN DANG CORP (KR) | 1998-10-14 | — | — | EP | disclosed |
| WO-1996012716-A1 | NUCLEOSIDE DERIVATIVES AND PROCESS FOR PREPARING THEREOF | CHONG KUN DANG CORP. (KR) | 1996-05-02 | — | — | WO | disclosed |