Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.92 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16735819 | 1.00 | TLR7 (0.92) | TLR7 | |
| SCHEMBL30575442 | 0.96 | TLR7 (1.00) | TLR7 | |
| SCHEMBL1527537 | 0.96 | TLR7 (1.00) | TLR7 | |
| SCHEMBL173521 | 0.96 | TLR7 (1.00) | TLR7 | |
| SCHEMBL30575438 | 0.96 | TLR7 (1.00) | TLR7 | |
| SCHEMBL30575432 | 0.94 | TLR7 (0.98) | TLR7 | |
| SCHEMBL173264 | 0.94 | TLR7 (0.98) | TLR7 | |
| SCHEMBL1527631 | 0.93 | TLR7 (1.00) | TLR7 | |
| SCHEMBL170115 | 0.93 | TLR7 (1.00) | TLR7 | |
| SCHEMBL30575428 | 0.93 | TLR7 (1.00) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268618-B1 | COMPOUNDS AND COMPOSITIONS AS TLR ACTIVITY MODULATORS | NOVARTIS AG (CH) | 2015-05-27 | — | — | EP | claimed |
| EP-2440245-A1 | BENZONAPHTHYRIDINE-CONTAINING VACCINES | Novartis AG (CH) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010144734-A1 | BENZONAPHTHYRIDINE-CONTAINING VACCINES | NOVARTIS AG (CH) | 2010-12-16 | — | — | WO | disclosed |