Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 13/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | CCR4 | P51679 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30843230 | 0.84 | LMNA (0.46) | PTGER4ALDH1A1TYK2PTGER2CNR1 | |
| SCHEMBL30989977 | 0.84 | DHODH (0.42) | PTGER4ALDH1A1PTGER2DHODHCYP1A2 | |
| SCHEMBL30990022 | 0.84 | DHODH (0.42) | PTGER4ALDH1A1PTGER2DHODHCYP1A2 | |
| SCHEMBL30843211 | 0.82 | TYK2 (0.44) | PTGER4ALDH1A1TYK2PTGER2CNR1 | |
| SCHEMBL9653496 | 0.81 | KDM4E (0.45) | PTGER4ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30990017 | 0.81 | KDM4E (0.45) | PTGER4ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11551863 | 0.81 | PTGER1 (0.43) | PTGER4PTGER2DHODHCYP3A4CYP2C9 | |
| SCHEMBL4018803 | 0.79 | MAPK1 (0.43) | PTGER4ALDH1A1PTGER2S1PR1S1PR5 | |
| SCHEMBL11463145 | 0.79 | KMT2A (0.49) | PTGER4ALDH1A1PTGER2CYP1A2CYP3A4 | |
| SCHEMBL30990046 | 0.79 | KMT2A (0.49) | PTGER4ALDH1A1PTGER2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015125785-A1 | PYRAZOLONE DERIVATIVE HAVING MULTIPLE SUBSTITUENTS | 第一三共株式会社 | 2015-08-27 | — | — | WO | disclosed |