Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2B6 | P20813 | 3/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.37 |
| ▸ | ITGAL | P20701 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 2/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28110506 | 0.98 | CYP2B6 (0.40) | CYP2B6STSABCG2ITGB2ICAM1 | |
| SCHEMBL27866473 | 0.98 | CYP2B6 (0.40) | CYP2B6STSABCG2ITGB2ICAM1 | |
| SCHEMBL28041420 | 0.98 | CYP2B6 (0.40) | CYP2B6STSABCG2ITGB2ICAM1 | |
| SCHEMBL28201961 | 0.98 | CYP2B6 (0.40) | CYP2B6STSABCG2ITGB2ICAM1 | |
| SCHEMBL3406847 | 0.98 | CYP2B6 (0.40) | CYP2B6STSABCG2ITGB2ICAM1 | |
| SCHEMBL39997 | 0.98 | CYP2B6 (0.42) | CYP2B6STSABCG2ITGB2ICAM1 | |
| SCHEMBL27797815 | 0.98 | CYP2B6 (0.42) | CYP2B6STSABCG2ITGB2ICAM1 | |
| SCHEMBL30285 | 0.98 | CYP2B6 (0.42) | CYP2B6STSABCG2ITGB2ICAM1 | |
| SCHEMBL29846230 | 0.98 | CYP2B6 (0.42) | CYP2B6STSABCG2ITGB2ICAM1 | |
| SCHEMBL6862607 | 0.96 | CYP2B6 (0.39) | CYP2B6STSABCG2ITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2310 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3181271-B1 | THREE-DIMENSIONAL SHAPED ARTICLE PRODUCTION METHOD, THREE-DIMENSIONAL SHAPED ARTICLE PRODUCTION APPARATUS, AND THREE-DIMENSIONAL SHAPED ARTICLE | SEIKO EPSON CORP (JP) | 2024-07-17 | — | — | EP | claimed |
| EP-4161448-B1 | UNICOMPARTIMENTAL KNEE PROSTHESIS | GRUPPO BIOIMPIANTI S R L (IT) | 2024-07-10 | — | — | EP | claimed |
| CN-221205795-U | Novel customized 3D prints anatomic type full wrist joint prosthesis | 西南医科大学附属医院 | 2024-06-25 | — | — | CN | claimed |
| CN-117679140-A | Test mold for magnesium metal bone screw and use method thereof | 苏州卓恰医疗科技有限公司 | 2024-03-12 | — | — | CN | claimed |
| US-20240041612-A1 | TOTAL SPINAL JOINT SYSTEMS WITH MOTION MODERATORS | 3SPINE INC (US) | 2024-02-08 | — | — | US | claimed |
| CN-117426907-A | Personalized first metacarpal prosthesis | 北京市春立正达医疗器械股份有限公司 | 2024-01-23 | — | — | CN | claimed |
| CN-117323036-A | Cobalt-chromium-molybdenum bracket denture of resin denture and preparation method thereof | 深圳新致美精密齿研有限公司 | 2024-01-02 | — | — | CN | claimed |
| US-20230380984-A1 | TOTAL SPINAL JOINT SYSTEMS WITH DISSIMILAR BEARING MATERIALS | 3SPINE INC (US) | 2023-11-30 | — | — | US | claimed |
| US-20230363925-A1 | INTERVERTEBRAL SPACER THAT DYNAMICALLY PROMOTES BONE GROWTH | SIMPLIFY MEDICAL PTY LTD (AU) | 2023-11-16 | — | — | US | claimed |
| EP-4122427-B1 | ENDOPROSTHETIC ROTATING HINGE KNEE ASSEMBLIES AND SUBASSEMBLIES | MICROPORT ORTHOPEDICS HOLDINGS INC (US) | 2023-11-15 | — | — | EP | claimed |
| WO-1991018561-A1 | FEMORAL STEM PROSTHESIS | ELTING, JAMES, J. (US) | 1991-12-12 | — | — | WO | claimed |
| US-4944754-A | Coating with crystalline hydroxyapatite | VENT-PLANT CORPORATION (US) | 1990-07-31 | — | — | US | claimed |
| US-4908030-A | Method of manufacturing synthetic bone coated surgical implants | VENT-PLANT CORPORATION, INC. (US) | 1990-03-13 | — | — | US | claimed |
| WO-1988008460-A1 | METHOD OF MANUFACTURING SYNTHETIC BONE COATED SURGICAL IMPLANTS | VENT-PLANT CORPORATION (US) | 1988-11-03 | — | — | WO | claimed |
| EP-0282161-A1 | Artificial spinal disc | HEALTH & RESEARCH SERVICES INC. (CA) | 1988-09-14 | — | — | EP | claimed |
| US-4759769-A | Artificial spinal disc | HEALTH & RESEARCH SERVICES INC. (CA) | 1988-07-26 | — | — | US | claimed |
| US-4550450-A | Total shoulder prosthesis system | KINNETT JAMES G | 1985-11-05 | — | — | US | claimed |
| EP-0048247-B1 | ORTHOPAEDIC IMPLANTS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-07-11 | — | — | EP | claimed |
| EP-0048247-A1 | ORTHOPAEDIC IMPLANTS. | NAT RES DEV (GB) | 1982-03-31 | — | — | EP | claimed |
| WO-1981002668-A1 | ORTHOPAEDIC IMPLANTS | NAT RES DEV (GB) | 1981-10-01 | — | — | WO | claimed |