Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24809674 | 0.88 | TSHR (0.32) | TSHR | |
| SCHEMBL24658842 | 0.80 | — | — | |
| SCHEMBL26728540 | 0.75 | TSHR (0.31) | TSHR | |
| SCHEMBL22326903 | 0.75 | TSHR (0.31) | TSHR | |
| SCHEMBL777860 | 0.73 | TSHR (0.33) | TSHR | |
| SCHEMBL21017311 | 0.69 | TSHR (0.31) | TSHR | |
| SCHEMBL777162 | 0.67 | TSHR (0.38) | TSHR | |
| SCHEMBL8596831 | 0.67 | — | — | |
| SCHEMBL30087287 | 0.67 | TSHR (0.35) | TSHRCYP3A4NFKB1NPSR1 | |
| Hydrochloric Acid SCHEMBL8586868 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120136175-A1 | PROCESS FOR PREPARATION OF ALKYL SULFONE COMPOUNDS | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2012-05-31 | — | — | US | disclosed |
| EP-2441751-A1 | PROCESS FOR PREPARATION OF ALKYL SULFONE COMPOUNDS | Sumitomo Seika Chemicals CO. LTD. (JP) | 2012-04-18 | — | — | EP | disclosed |
| EP-0938529-B1 | SULFUR REMOVAL BY CATALYTIC DISTILLATION | BP CORP NORTH AMERICA INC (US) | 2004-11-03 | — | — | EP | disclosed |
| EP-0902822-B1 | SULFUR REMOVAL PROCESS | BP CORP NORTH AMERICA INC (US) | 2003-07-09 | — | — | EP | disclosed |
| US-6048451-A | CONVERTING AT LEAST A PORTION OF THE SULFUR-CONTAINING IMPURITIES TO SULFUR-CONTAINING PRODUCTS OF HIGHER BOILING POINT BY TREATMENT WITH AN ALKYLATING AGENT IN THE PRESENCE OF AN ACID CATALYST; FRACTIONAL DISTILLATION | BP AMOCO CORPORATION (US) | 2000-04-11 | — | — | US | disclosed |
| US-5863419-A | Sulfur removal by catalytic distillation | AMOCO CORPORATION (US) | 1999-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120136175-A1 | PROCESS FOR PREPARATION OF ALKYL SULFONE COMPOUNDS | SULT1A1, CBR1, SULT1E1 | TSHR 1331/4885CYP3A4 137/4885NFKB1 1283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.