Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.48 |
| ▸ | PREP | P48147 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.35 |
| ▸ | OGG1 | O15527 | 1/20 | 0.34 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17043184 | 1.00 | P2RX3 (0.48) | P2RX3PREPALDH1A1ADAMTS4ADAMTS5 | |
| SCHEMBL1307282 | 0.96 | P2RX3 (0.48) | P2RX3PREPALDH1A1ADAMTS4ADAMTS5 | |
| SCHEMBL1307287 | 0.96 | P2RX3 (0.48) | P2RX3PREPALDH1A1ADAMTS4ADAMTS5 | |
| SCHEMBL1306458 | 0.95 | P2RX3 (0.48) | P2RX3PREPALDH1A1ADAMTS4ADAMTS5 | |
| SCHEMBL1306464 | 0.95 | P2RX3 (0.48) | P2RX3PREPALDH1A1ADAMTS4ADAMTS5 | |
| SCHEMBL2893541 | 0.92 | P2RX3 (0.47) | P2RX3PREPALDH1A1ADAMTS4ADAMTS5 | |
| SCHEMBL2893536 | 0.92 | P2RX3 (0.47) | P2RX3PREPALDH1A1ADAMTS4ADAMTS5 | |
| SCHEMBL1306091 | 0.91 | P2RX3 (0.46) | P2RX3PREPALDH1A1ADAMTS4ADAMTS5 | |
| SCHEMBL1306086 | 0.91 | P2RX3 (0.46) | P2RX3PREPALDH1A1ADAMTS4ADAMTS5 | |
| SCHEMBL1307169 | 0.91 | P2RX3 (0.55) | P2RX3PREPALDH1A1ADAMTS4ADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2913322-A2 | Naphthalenyloxypropenyl derivatives having inhibitory activity against histone deacetylase and pharmaceutical composition comprising the same | Korea Research Institute Of Chemical Technology (KR) | 2015-09-02 | — | — | EP | disclosed |