Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 2/20 | 0.44 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | FADS1 | O60427 | 1/20 | 0.39 |
| ▸ | MELK | Q14680 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17044074 | 0.91 | RIPK2 (0.50) | GRM4PTK6RIPK2CA9EGFR | |
| SCHEMBL17044067 | 0.87 | KDM4E (0.44) | GRM4RIPK2TGFBR1PTGS2PTGS1 | |
| SCHEMBL17044092 | 0.85 | KDR (0.41) | PTK6RIPK2TGFBR1MEN1KMT2A | |
| SCHEMBL17044080 | 0.84 | GRM4 (0.43) | GRM4PTK6RIPK2CA9TGFBR1 | |
| SCHEMBL17044112 | 0.83 | GAA (0.45) | PTK6RIPK2EGFRPTGS1HTR1A | |
| SCHEMBL17044108 | 0.83 | MAPKAPK2 (0.49) | CA9MEN1KMT2ANPC1HSP90AA1 | |
| SCHEMBL17044086 | 0.81 | RIPK2 (0.43) | GRM4RIPK2MEN1KMT2ANPC1 | |
| SCHEMBL17044063 | 0.81 | KDR (0.46) | GRM4RIPK2MEN1KMT2ANPC1 | |
| SCHEMBL17044098 | 0.81 | RET (0.42) | GRM4MEN1KMT2ANPC1HSP90AA1 | |
| SCHEMBL17044069 | 0.79 | PTGS1 (0.45) | PTK6EGFRFADS1PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566477-B1 | AMINO-QUINOLINES AS KINASE INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2015-09-02 | — | — | EP | claimed |