Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17044485 | 1.00 | SMN1; SMN2 (0.58) | SMN1; SMN2HPGDMAPTLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL5703185 | 0.99 | SMN1; SMN2 (0.57) | SMN1; SMN2HPGDMAPTLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL5703189 | 0.99 | SMN1; SMN2 (0.57) | SMN1; SMN2HPGDMAPTLMNAKMT2A | |
| SCHEMBL7743096 | 0.90 | HPGD (0.68) | SMN1; SMN2HPGDMAPTLMNAKMT2A | |
| SCHEMBL7743100 | 0.90 | HPGD (0.68) | SMN1; SMN2HPGDMAPTLMNAKMT2A | |
| SCHEMBL19449737 | 0.89 | HPGD (0.58) | SMN1; SMN2HPGDMAPTLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL6515900 | 0.89 | HPGD (0.66) | SMN1; SMN2HPGDMAPTLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL6515894 | 0.89 | HPGD (0.66) | SMN1; SMN2HPGDMAPTLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL17560910 | 0.88 | HPGD (0.57) | SMN1; SMN2HPGDMAPTLMNAKMT2A | |
| SCHEMBL7743098 | 0.86 | MAPT (0.47) | SMN1; SMN2HPGDMAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150246140-A1 | COMPOSITIONS AND METHODS FOR MODULATING SLEEP AND WAKEFULNESS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2015-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150246140-A1 | COMPOSITIONS AND METHODS FOR MODULATING SLEEP AND WAKEFULNESS | HCRTR2, HCRTR1, NPSR1 | SMN1; SMN2 1337/4885HPGD 3943/4885MAPT 2646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.