SCHEMBL17047851

SCHEMBL17047851

O=C(O)c1ccccc1C(=O)/C=C/c1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 7/20 0.73
▸ BCHE P06276 2/20 0.70
▸ CYP2C19 P33261 1/20 0.70
▸ MAOB P27338 4/20 0.62
▸ CYP1B1 Q16678 3/20 0.62
▸ PLIN1 O60240 2/20 0.62
▸ LMNA P02545 2/20 0.62
▸ RECQL P46063 2/20 0.62
▸ PLIN5 Q00G26 2/20 0.62
▸ ABHD5 Q8WTS1 2/20 0.62
▸ TNFRSF1A P19438 1/20 0.62
▸ ACHE P22303 1/20 0.62
▸ ALDH1A1 P00352 4/20 0.57
▸ TDP1 Q9NUW8 4/20 0.57
▸ SMN1; SMN2 Q16637 3/20 0.57
▸ ALOX15 P16050 3/20 0.57
▸ MEN1 O00255 3/20 0.57
▸ CYP3A4 P08684 3/20 0.57
▸ KMT2A Q03164 3/20 0.57
▸ KDM4E B2RXH2 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31233508 1.00 MAPT (0.73) MAPTBCHECYP2C19MAOBCYP1B1
SCHEMBL17047852 1.00 MAPT (0.73) MAPTBCHECYP2C19MAOBCYP1B1
SCHEMBL25202121 1.00 MAPT (0.73) MAPTBCHECYP2C19MAOBCYP1B1
SCHEMBL30383301 1.00 MAPT (0.73) MAPTBCHECYP2C19MAOBCYP1B1
SCHEMBL30382962 0.89 MAPT (0.60) MAPTBCHECYP2C19MAOBCYP1B1
SCHEMBL25190924 0.89 MAPT (0.73) MAPTBCHECYP2C19MAOBCYP1B1
SCHEMBL12700438 0.89 MAPT (0.60) MAPTBCHECYP2C19MAOBCYP1B1
SCHEMBL25184971 0.89 MAPT (0.60) MAPTBCHECYP2C19MAOBCYP1B1
SCHEMBL25221715 0.88 MAOB (0.71) MAPTBCHECYP2C19MAOBCYP1B1
SCHEMBL25195679 0.88 MAOB (0.71) MAPTBCHECYP2C19MAOBCYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed
EP-3110392-B1 TOPICAL COSMETIC OR PHARMACEUTICAL COMPOSITION LVS CAPITAL GMBH (DE) 2020-11-25 — — EP disclosed
EP-3110392-A1 TOPICAL COSMETIC OR PHARMACEUTICAL COMPOSITION LVS-Capital GmbH (DE) 2017-01-04 — — EP disclosed
WO-2015128280-A1 TOPICAL COSMETIC OR PHARMACEUTICAL COMPOSITION LVS-CAPITAL GMBH (DE) 2015-09-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAPT 3297/4885BCHE 588/4885CYP2C19 109/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885BCHE 465/4885CYP2C19 583/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885BCHE 465/4885CYP2C19 583/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback