⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2923103 | 0.81 | — | — | |
| SCHEMBL27850208 | 0.79 | — | — | |
| SCHEMBL10865711 | 0.75 | — | — | |
| SCHEMBL2994011 | 0.75 | — | — | |
| SCHEMBL10012495 | 0.75 | — | — | |
| SCHEMBL7690769 | 0.75 | — | — | |
| SCHEMBL2605833 | 0.75 | — | — | |
| SCHEMBL7756628 | 0.75 | — | — | |
| SCHEMBL29914241 | 0.75 | — | — | |
| SCHEMBL9937577 | 0.72 | NOTUM (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3510404-A1 | CHEMICAL PROBES OF LYSYL OXIDASE-LIKE 2 AND USES THEREOF | Pharmakea, Inc. (US) | 2019-07-17 | — | — | EP | claimed |
| US-20190192697-A1 | CHEMICAL PROBES OF LYSYL OXIDASK-LIKE 2 AND USES THEREOF | PHARMAKEA, INC. | 2019-06-27 | — | — | US | claimed |
| WO-2018048928-A1 | CHEMICAL PROBES OF LYSYL OXIDASE-LIKE 2 AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | claimed |
| WO-2018048930-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | claimed |
| US-20140235548-A1 | COMPOSITIONS AND METHODS FOR JAMM PROTEIN INHIBITION | CLEAVE BIOSCIENCES, INC. (US) | 2014-08-21 | — | — | US | claimed |
| EP-2710119-A1 | COMPOSITIONS AND METHODS FOR JAMM PROTEIN INHIBITION | Cleave Biosciences, Inc. (US) | 2014-03-26 | — | — | EP | claimed |
| WO-2012158435-A1 | COMPOSITIONS AND METHODS FOR JAMM PROTEIN INHIBITION | ZHOU HAN-JIE (US) | 2012-11-22 | — | — | WO | claimed |
| EP-3510404-A1 | CHEMICAL PROBES OF LYSYL OXIDASE-LIKE 2 AND USES THEREOF | Pharmakea, Inc. (US) | 2019-07-17 | — | — | EP | disclosed |
| US-20190192697-A1 | CHEMICAL PROBES OF LYSYL OXIDASK-LIKE 2 AND USES THEREOF | PHARMAKEA, INC. | 2019-06-27 | — | — | US | disclosed |
| WO-2018048930-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | disclosed |
| WO-2018048928-A1 | CHEMICAL PROBES OF LYSYL OXIDASE-LIKE 2 AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | disclosed |
| US-20140235548-A1 | COMPOSITIONS AND METHODS FOR JAMM PROTEIN INHIBITION | CLEAVE BIOSCIENCES, INC. (US) | 2014-08-21 | — | — | US | disclosed |
| US-20140221427-A1 | ISOTOPOLOGUES OF POMALIDOMIDE | CELGENE CORPORATION (US) | 2014-08-07 | — | — | US | disclosed |
| CN-1671689-A | Pyridyl-triazine derivatives as microbicidal active substances | CIBA SC HOLDING AG (CH) | 2005-09-21 | — | — | CN | disclosed |
| EP-1525196-A1 | PYRIDYL-TRIAZINE DERIVATIVES AS MICROBICIDAL ACTIVE SUBSTANCES | Ciba SC Holding AG (CH) | 2005-04-27 | — | — | EP | disclosed |
| WO-2004013124-A1 | PYRIDYL-TRIAZINE DERIVATIVES AS MICROBICIDAL ACTIVE SUBSTANCES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-02-12 | — | — | WO | disclosed |
| US-4897108-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-01-30 | — | — | US | disclosed |
| US-4769060-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-09-06 | — | — | US | disclosed |
| US-4661147-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-04-28 | — | — | US | disclosed |
| EP-0165003-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-12-18 | — | — | EP | disclosed |