Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 13/20 | 0.67 |
| ▸ | P2RX1 | P51575 | 8/20 | 0.62 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.62 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.62 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | IKBKB | O14920 | 1/20 | 0.59 |
| ▸ | CHUK | O15111 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | FLT3 | P36888 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | MYLK | Q15746 | 1/20 | 0.59 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30771722 | 0.87 | P2RX1 (0.68) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL18341338 | 0.87 | P2RX1 (0.68) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL30771738 | 0.83 | TMPRSS4 (0.73) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL329995 | 0.83 | TMPRSS4 (0.73) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL14886017 | 0.82 | TMPRSS4 (0.65) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL330187 | 0.82 | TMPRSS4 (0.65) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL330371 | 0.81 | TMPRSS4 (0.68) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL14885891 | 0.80 | TMPRSS4 (1.00) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL4264823 | 0.80 | TMPRSS4 (0.72) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL30771732 | 0.79 | P2RX1 (0.64) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844766-B1 | Inhibitors against the production and release of inflammatory cytokines | INST MED MOLECULAR DESIGN INC (JP) | 2012-04-18 | — | — | EP | disclosed |