Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 12/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17049298 | 0.88 | HTR6 (0.56) | HTR6MEN1KMT2AL3MBTL1HTT | |
| SCHEMBL1898211 | 0.88 | HTR6 (0.56) | HTR6MEN1KMT2ASLC1A3SLC1A2 | |
| SCHEMBL2573218 | 0.82 | MEN1 (0.60) | HTR6MEN1KMT2ASLC1A3SLC1A2 | |
| SCHEMBL1892821 | 0.82 | HTR6 (0.54) | HTR6MEN1KMT2ASLC1A3SLC1A2 | |
| SCHEMBL1306928 | 0.82 | HTR6 (0.54) | HTR6MEN1KMT2ASLC1A3SLC1A2 | |
| SCHEMBL29408218 | 0.82 | MEN1 (0.60) | HTR6MEN1KMT2ASLC1A3SLC1A2 | |
| SCHEMBL22980669 | 0.80 | HTR6 (0.78) | HTR6MEN1KMT2ASLC1A3SLC1A2 | |
| SCHEMBL1892670 | 0.80 | HTR6 (0.78) | HTR6MEN1KMT2ASLC1A3SLC1A2 | |
| SCHEMBL2134757 | 0.80 | CYP2A6 (0.51) | HTR6MEN1KMT2ASLC1A3SLC1A2 | |
| SCHEMBL18161364 | 0.80 | HTR6 (0.49) | HTR6MEN1KMT2ASLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022187693-A1 | COVALENT CDK2-BINDING COMPOUNDS FOR THERAPEUTIC PURPOSES | UMBRA THERAPEUTICS INC. (US) | 2022-09-09 | — | — | WO | disclosed |
| WO-2015131100-A1 | LIGAND-CONTROLLED C(SP3)-H ARYLATION AND OLEFINATION IN SYNTHESIS OF UNNATURAL CHIRAL ALPHA AMINO ACIDS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-09-03 | — | — | WO | disclosed |