Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17049335 | 1.00 | MEN1 (0.47) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL17049236 | 0.89 | KMT2A (0.50) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL17049312 | 0.87 | KMT2A (0.50) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL17049329 | 0.87 | KMT2A (0.46) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL17049250 | 0.86 | KMT2A (0.44) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL17049252 | 0.86 | KMT2A (0.44) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL17049257 | 0.84 | MEN1 (0.53) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL17049350 | 0.84 | MEN1 (0.42) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL17049281 | 0.82 | ALDH1A1 (0.49) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL17049279 | 0.82 | ALDH1A1 (0.49) | MEN1KMT2AMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015131100-A1 | LIGAND-CONTROLLED C(SP3)-H ARYLATION AND OLEFINATION IN SYNTHESIS OF UNNATURAL CHIRAL ALPHA AMINO ACIDS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-09-03 | — | — | WO | disclosed |