Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 10/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10248751 | 0.83 | MEN1 (0.54) | STSMEN1KMT2AMAPTGPR119 | |
| SCHEMBL31043013 | 0.80 | STS (0.53) | STSPTPN2PTPN1PTPN6HPGD | |
| SCHEMBL23165969 | 0.77 | STS (0.46) | STSPTPN2PTPN1PTPN6HPGD | |
| SCHEMBL13390978 | 0.77 | STS (0.61) | STSPTPN2PTPN1PTPN6HPGD | |
| SCHEMBL15534854 | 0.76 | KDM4E (0.54) | STSHPGDMEN1USP2KMT2A | |
| SCHEMBL473345 | 0.76 | STS (0.67) | STSMEN1KMT2A | |
| SCHEMBL26967674 | 0.76 | STS (0.49) | STSHPGDMEN1USP2KMT2A | |
| SCHEMBL21605851 | 0.75 | GPR119 (0.55) | STSPTPN2PTPN1PTPN6HPGD | |
| SCHEMBL31462554 | 0.75 | STS (0.58) | STSPTPN2PTPN1PTPN6HPGD | |
| SCHEMBL5705838 | 0.75 | STS (0.58) | STSPTPN2PTPN1PTPN6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9120752-B2 | Pyridine compounds as sodium channel blockers | PURDUE PHARMA, L.P. (US) | 2015-09-01 | — | — | US | disclosed |
| US-9120752-B2 | Pyridine compounds as sodium channel blockers | PURDUE PHARMA, L.P. (US) | 2015-09-01 | — | — | US | disclosed |