Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17049461 | 0.97 | ACACB (0.55) | ACACBALDH1A1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL17049471 | 0.93 | ACACB (0.58) | ACACBALDH1A1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL2623651 | 0.91 | ACACB (0.46) | ACACBALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL17049462 | 0.89 | ACACB (0.54) | ACACBALDH1A1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL17049470 | 0.88 | ACACB (0.58) | ACACBALDH1A1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL17049463 | 0.88 | ACACB (0.53) | ACACBALDH1A1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL13302477 | 0.88 | ACACB (0.45) | ACACBALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL17049460 | 0.87 | ACACB (0.57) | ACACBALDH1A1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL16799896 | 0.84 | ACACB (0.40) | ACACBALDH1A1RAB9AHPGDNPC1 | |
| SCHEMBL16799894 | 0.84 | ACACB (0.40) | ACACBALDH1A1RAB9AHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9120723-B2 | Modulator | CANBEX THERAPEUTICS LIMITED (GB) | 2015-09-01 | — | — | US | disclosed |