Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17049459 | 0.97 | ACACB (0.56) | ACACBALDH1A1RAB9AMMP2MMP12 | |
| SCHEMBL17049471 | 0.92 | ACACB (0.58) | ACACBALDH1A1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL13302477 | 0.91 | ACACB (0.45) | ACACBALDH1A1MMP2MMP12LMNA | |
| SCHEMBL2623651 | 0.88 | ACACB (0.46) | ACACBALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL17049470 | 0.87 | ACACB (0.58) | ACACBALDH1A1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL17049460 | 0.86 | ACACB (0.57) | ACACBALDH1A1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL17049462 | 0.86 | ACACB (0.54) | ACACBALDH1A1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL17049463 | 0.85 | ACACB (0.53) | ACACBALDH1A1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL16799931 | 0.84 | POLB (0.42) | ACACBALDH1A1RAB9AMMP2MMP12 | |
| SCHEMBL16799929 | 0.84 | POLB (0.42) | ACACBALDH1A1RAB9AMMP2MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9120723-B2 | Modulator | CANBEX THERAPEUTICS LIMITED (GB) | 2015-09-01 | — | — | US | disclosed |