Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.73 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.73 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.73 |
| ▸ | MAP1LC3A | Q9H492 | 2/20 | 0.73 |
| ▸ | POLQ | O75417 | 1/20 | 0.73 |
| ▸ | ALB | P02768 | 1/20 | 0.73 |
| ▸ | KDR | P35968 | 1/20 | 0.73 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21363200 | 1.00 | HSP90AB1 (0.73) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL10306489 | 1.00 | HSP90AB1 (0.73) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL13644903 | 1.00 | HSP90AB1 (0.73) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL6935655 | 1.00 | HSP90AB1 (0.73) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL24589015 | 0.92 | HSP90AB1 (0.68) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL22023535 | 0.91 | HSP90AB1 (0.68) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL21363030 | 0.91 | HSP90AB1 (0.68) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL22023815 | 0.91 | HSP90AB1 (0.68) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL21363211 | 0.91 | HSP90AB1 (0.67) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL21362996 | 0.90 | HSP90AB1 (0.67) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2438078-B1 | NOVOBIOCIN ANALOGUES HAVING MODIFIED SUGAR MOIETIES | UNIV KANSAS (US) | 2017-10-25 | — | — | EP | disclosed |
| US-9120774-B2 | Novobiocin analogues having modified sugar moieties | UNIVERSITY OF KANSAS (US) | 2015-09-01 | — | — | US | disclosed |