Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.68 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.68 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.68 |
| ▸ | MAP1LC3A | Q9H492 | 2/20 | 0.68 |
| ▸ | POLQ | O75417 | 1/20 | 0.68 |
| ▸ | ALB | P02768 | 1/20 | 0.68 |
| ▸ | KDR | P35968 | 1/20 | 0.68 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22023535 | 1.00 | HSP90AB1 (0.68) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL22023815 | 1.00 | HSP90AB1 (0.68) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL24589015 | 0.93 | HSP90AB1 (0.68) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL17049899 | 0.91 | HSP90AB1 (0.73) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL10306489 | 0.91 | HSP90AB1 (0.73) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL6935655 | 0.91 | HSP90AB1 (0.73) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL13644903 | 0.91 | HSP90AB1 (0.73) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL21363200 | 0.91 | HSP90AB1 (0.73) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL21363092 | 0.89 | HSP90AB1 (0.56) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL21363211 | 0.88 | HSP90AB1 (0.67) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11713335-B2 | Aminocoumarin compounds and methods of their use | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-08-01 | — | — | US | disclosed |
| US-20210009621-A1 | AMINOCOUMARIN COMPOUNDS AND METHODS OF THEIR USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2021-01-14 | — | — | US | disclosed |
| WO-2019178119-A1 | AMINOCOUMARIN COMPOUNDS AND METHODS OF THEIR USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210009621-A1 | AMINOCOUMARIN COMPOUNDS AND METHODS OF THEIR USE | AAAS, PROC, AADAC | HSP90AB1 1341/4885HSP90AA1 1344/4885MAP1LC3B 3338/4885 |
| US-11713335-B2 | Aminocoumarin compounds and methods of their use | AAAS, PROC, AADAC | HSP90AB1 1341/4885HSP90AA1 1344/4885MAP1LC3B 3338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.