Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3695983 | 0.92 | CES1 (0.43) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL7131338 | 0.82 | CES2 (0.55) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL10401052 | 0.82 | CES2 (0.55) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL11036678 | 0.82 | CES2 (0.55) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL9813357 | 0.79 | CES2 (0.61) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL3108058 | 0.79 | CES2 (0.61) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL5708415 | 0.79 | CES2 (0.61) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL2352905 | 0.79 | CES2 (0.61) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL3108046 | 0.79 | CES2 (0.61) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL17504241 | 0.79 | CES2 (0.61) | CES2MEN1FAAHMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173350-B1 | STEREOSELECTIVE PROCESS FOR PREPARING PURINE DIOXOLANE NUCLEOSIDE DERIVATIVES | RFS PHARMA LLC (US) | 2012-04-18 | — | — | EP | claimed |