SCHEMBL17050256

SCHEMBL17050256

CCC1(CCC2(CCC(=O)O)c3ccccc3-c3ccccc32)c2ccccc2-c2ccccc21

nearest known ligand 0.81

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.81
THRB P10828 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
PGR P06401 2/20 0.37
PDK2 Q15119 4/20 0.36
NPC1 O15118 1/20 0.36
CYP2C19 P33261 1/20 0.35
KEAP1 Q14145 1/20 0.35
MAP2K7 O14733 1/20 0.35
CDC25A P30304 1/20 0.35
CDC25B P30305 1/20 0.35
NR4A2 P43354 1/20 0.34
ELANE P08246 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15691725 0.92 APEX1 (0.96) APEX1THRBTDP1PDK2NPC1
SCHEMBL5866539 0.90 APEX1 (1.00) APEX1THRBTDP1PDK2NPC1
SCHEMBL29512333 0.90 APEX1 (1.00) APEX1THRBTDP1PDK2NPC1
SCHEMBL29512337 0.90 APEX1 (1.00) APEX1THRBTDP1PDK2NPC1
SCHEMBL29441930 0.90 APEX1 (1.00) APEX1THRBTDP1PDK2NPC1
SCHEMBL17050245 0.89 APEX1 (0.73) APEX1THRBTDP1PGRPDK2
SCHEMBL24179777 0.83 APEX1 (0.86) APEX1THRBTDP1PDK2NPC1
SCHEMBL5990939 0.83 APEX1 (0.73) APEX1TDP1CYP2C19
SCHEMBL15691574 0.83 APEX1 (0.86) APEX1THRBTDP1PDK2NPC1
SCHEMBL18663270 0.81 APEX1 (0.83) APEX1THRBTDP1PDK2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9518150-B2 Resin composition, stretched film, circularly polarizing plate, and image display device MITSUBISHI CHEMICAL CORPORATION (JP) 2016-12-13 US disclosed
US-20150247002-A1 RESIN COMPOSITION, STRETCHED FILM, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2015-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150247002-A1 RESIN COMPOSITION, STRETCHED FILM, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE RAD50, RAD54L, PUF60 APEX1 3376/4885THRB 3988/4885TDP1 3587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.