Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.73 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 6/20 | 0.42 |
| ▸ | PPARD | Q03181 | 6/20 | 0.42 |
| ▸ | PPARA | Q07869 | 6/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3970295 | 0.86 | APEX1 (0.74) | APEX1HDAC11TSHRALDH1A1TDP1 | |
| SCHEMBL29506870 | 0.86 | APEX1 (0.74) | APEX1HDAC11TSHRALDH1A1TDP1 | |
| SCHEMBL1395294 | 0.86 | APEX1 (0.47) | APEX1MMP2MMP9MMP8MMP13 | |
| SCHEMBL6060916 | 0.86 | APEX1 (0.47) | APEX1MMP2MMP9MMP8MMP13 | |
| SCHEMBL5866539 | 0.86 | APEX1 (1.00) | APEX1CYP2C19HDAC11TSHRALDH1A1 | |
| SCHEMBL17034549 | 0.86 | APEX1 (0.47) | APEX1MMP2MMP9MMP8MMP13 | |
| SCHEMBL6060794 | 0.86 | APEX1 (0.47) | APEX1MMP2MMP9MMP8MMP13 | |
| SCHEMBL1681761 | 0.86 | APEX1 (0.47) | APEX1MMP2MMP9MMP8MMP13 | |
| SCHEMBL6060635 | 0.86 | APEX1 (0.47) | APEX1MMP2MMP9MMP8MMP13 | |
| SCHEMBL6060689 | 0.86 | APEX1 (0.47) | APEX1MMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130027636-A1 | CLASS OF BRIDGED BIPHENYLENE POLYMERS | SUMITOMO CHEMICAL CO., LTD. (JP) | 2013-01-31 | — | — | US | disclosed |
| US-20060094859-A1 | Class of bridged biphenylene polymers | SUMITOMO CHEMICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |