Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 4/20 | 0.35 |
| ▸ | APAF1 | O14727 | 2/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15691740 | 0.91 | APEX1 (0.49) | APEX1THRBTDP1KIF11APAF1 | |
| SCHEMBL17050329 | 0.90 | APEX1 (0.50) | APEX1PGRTHRBTDP1KIF11 | |
| SCHEMBL21219235 | 0.85 | APEX1 (0.51) | APEX1THRBTDP1KIF11APAF1 | |
| SCHEMBL29441927 | 0.85 | APEX1 (0.51) | APEX1THRBTDP1KIF11APAF1 | |
| SCHEMBL17050347 | 0.80 | APEX1 (0.41) | APEX1PGRTHRBTDP1KIF11 | |
| SCHEMBL24349730 | 0.77 | PDK2 (0.50) | APEX1TDP1APAF1PDK2CYP1A2 | |
| SCHEMBL15691750 | 0.76 | THRB (0.44) | APEX1THRBTDP1KIF11APAF1 | |
| SCHEMBL15691751 | 0.75 | APEX1 (0.41) | APEX1THRBTDP1PDK2CYP2C19 | |
| SCHEMBL15691752 | 0.75 | APEX1 (0.42) | APEX1THRBTDP1PDK2POLB | |
| SCHEMBL26017050 | 0.75 | APEX1 (0.42) | APEX1THRBTDP1KIF11APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9518150-B2 | Resin composition, stretched film, circularly polarizing plate, and image display device | MITSUBISHI CHEMICAL CORPORATION (JP) | 2016-12-13 | — | — | US | disclosed |
| US-20150247002-A1 | RESIN COMPOSITION, STRETCHED FILM, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2015-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150247002-A1 | RESIN COMPOSITION, STRETCHED FILM, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE | RAD50, RAD54L, PUF60 | APEX1 3376/4885PGR 3513/4885THRB 3988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.